PNPP
PNPP structure
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Common Name | PNPP | ||
|---|---|---|---|---|
| CAS Number | 4264-83-9 | Molecular Weight | 219.089 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 457.8±47.0 °C at 760 mmHg | |
| Molecular Formula | C6H4NNa2O6P | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 230.7±29.3 °C | |
| Symbol |
GHS05, GHS08 |
Signal Word | Danger | |
Use of PNPPPNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Disodium 4-nitrophenylphosphate |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | PNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. |
|---|---|
| Related Catalog | |
| In Vitro | Phosphatases catalyze the hydrolysis of PNPP liberating inorganic phosphate and the conjugate base of para-nitrophenol (pNP). The resulting phenolate is yellow, with a maximal absorption at 405 nm[1]. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 457.8±47.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Molecular Formula | C6H4NNa2O6P |
| Molecular Weight | 219.089 |
| Flash Point | 230.7±29.3 °C |
| Exact Mass | 218.993271 |
| PSA | 128.05000 |
| LogP | 0.37 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.617 |
| InChIKey | VIYFPAMJCJLZKD-UHFFFAOYSA-L |
| SMILES | O=[N+]([O-])c1ccc(OP(=O)([O-])[O-])cc1.[Na+].[Na+] |
| Storage condition | 2-8°C |
| Stability | Stable, but may be light sensitive. Incompatible with strong acids, strong bases, strong oxidizing agents. |
| Water Solubility | H2O: 1 tablet/3 mL 25 mM, clear, light yellow |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS05, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H290-H315-H318-H373 |
| Precautionary Statements | P260-P280-P305 + P351 + P338 + P310 |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25-S23 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2919900090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~52%
PNPP CAS#:4264-83-9 |
| Literature: Schiller, Alexander; Scopelliti, Rosario; Severin, Kay Dalton Transactions, 2006 , # 32 p. 3858 - 3867 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
|---|---|
| DownStream 1 | |
CAS#:14609-74-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2919900090 |
|---|---|
| Summary | 2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Enhancement of enzymatic colorimetric response by silver island films on high throughput screening microplates.
J. Immunol. Methods 411 , 43-9, (2014) In this study, we report the use of an enzyme-based hybrid platform, which is comprised of silver island films, enzymes (HRP and AP) and high-throughput screening (HTS) microplates, to enhance the col... |
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Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor.
Biotechnol. Bioeng. 112(2) , 308-21, (2015) Tobacco BY-2 cells have emerged as a promising platform for the manufacture of biopharmaceutical proteins, offering efficient protein secretion, favourable growth characteristics and cultivation in co... |
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Sprayed cells and polyelectrolyte films for biomaterial functionalization: the influence of physical PLL-PGA film treatments on dental pulp cell behavior.
Macromol. Biosci. 14(12) , 1771-82, (2014) Further development of biomaterials is expected as advanced therapeutic products must be compliant to good manufacturing practice regulations. A spraying method for building-up polyelectrolyte films f... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Nitrophenyl dihydrogen phosphate |
| disodium,(4-nitrophenyl) phosphate |
| 4-Nitrophenylphosphoric Acid Disodium Salt |
| 4-Nitrophenyl phosphate disodium salt |
| Phosphoric acid mono(4-nitrophenyl) ester |
| 4-Nitrophenyl phosphate disodium salt hexahydrate |
| p-Nitrophenyl Phosphate Liquid Substrate System |
| p-nitro-Phenol dihydrogen phosphate |
| 4-Nitrophenyl phosphate,disodium salt,hexahydrate |
| para-Nitrophenylphosphate |
| EINECS 224-246-5 |
| MFCD00007319 |
| Phosphoric acid mono(p-nitrophenyl) ester |
| Phosphoric acid, mono(4-nitrophenyl) ester |
| Sodium 4-nitrophenyl phosphate |
| PNPP |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of Disodium 4-nitrophenylphosphate? |
| A: LogP of Disodium 4-nitrophenylphosphate is 0.37. |
| Q: What is the safety information for Disodium 4-nitrophenylphosphate? |
| A: Safety information for Disodium 4-nitrophenylphosphate: S26-S36-S24/25-S23. |
| Q: What is the SMILES notation of Disodium 4-nitrophenylphosphate? |
| A: SMILES notation of Disodium 4-nitrophenylphosphate is O=[N+]([O-])c1ccc(OP(=O)([O-])[O-])cc1.[Na+].[Na+]. |
| Q: What are the downstream products of Disodium 4-nitrophenylphosphate? |
| A: Related downstream products(CAS) of Disodium 4-nitrophenylphosphate: 14609-74-6. |
| Q: What are the upstream materials of Disodium 4-nitrophenylphosphate? |
| A: Related upstream materials(CAS) of Disodium 4-nitrophenylphosphate: 4043-96-3. |
| Q: What are the uses of Disodium 4-nitrophenylphosphate? |
| A: Main uses of Disodium 4-nitrophenylphosphate: PNPP is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays. |
| Q: What is the boiling point of Disodium 4-nitrophenylphosphate? |
| A: Boiling point of Disodium 4-nitrophenylphosphate is 457.8±47.0 °C at 760 mmHg. |
| Q: What is the melting point of Disodium 4-nitrophenylphosphate? |
| A: Melting point of Disodium 4-nitrophenylphosphate is >300 °C(lit.). |
| Q: How is the water solubility of Disodium 4-nitrophenylphosphate? |
| A: Water solubility of Disodium 4-nitrophenylphosphate: H2O: 1 tablet/3 mL 25 mM, clear, light yellow. |
| Q: What is the polar surface area (PSA) of Disodium 4-nitrophenylphosphate? |
| A: Polar surface area (PSA) of Disodium 4-nitrophenylphosphate is 128.05000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |
| Zhongshan Xingrui Chemical Co. , Ltd. |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PNPP
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Disodium 4-nitrophenylphosphate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: TIANFUCHEM--4264-83-9--Disodium 4-nitrophenylphosphate factory price
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: PNPP
- Price: ￥Inquiry/25kg
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Wang Jie
- Email: 3096638339@qq.com
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