chloro-3-pyridylsulfone

Modify Date: 2024-01-11 20:51:01

chloro-3-pyridylsulfone Structure
chloro-3-pyridylsulfone structure
Common Name chloro-3-pyridylsulfone
CAS Number 42899-76-3 Molecular Weight 177.609
Density 1.5±0.1 g/cm3 Boiling Point 284.2±13.0 °C at 760 mmHg
Molecular Formula C5H4ClNO2S Melting Point 120-126ºC
MSDS Chinese USA Flash Point 125.7±19.8 °C

 Names

Name 3-Pyridinesulfonyl chloride, HCl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 284.2±13.0 °C at 760 mmHg
Melting Point 120-126ºC
Molecular Formula C5H4ClNO2S
Molecular Weight 177.609
Flash Point 125.7±19.8 °C
Exact Mass 176.965118
PSA 55.41000
LogP 0.89
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.553
Storage condition Store below -20C
Water Solubility Reacts with water.

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 3-Pyridinesulfonyl chloride, HCl
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H314:Causes severe skin burns and eye damage
H317:May cause an allergic skin reaction
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P310:Immediately call a POISON CENTER or doctor/physician

Section3. Composition/information on ingredients.
Ingredient name:3-Pyridinesulfonyl chloride, HCl
CAS number:42899-76-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
Eye contact:
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, under −20◦C.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
No data
Boiling point:
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C5H4ClNO2S.HCl
Molecular weight: 214.1

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN1759Class: 8Packing group: II
Proper shipping name: CORROSIVE SOLIDS, N.O.S. (3-Pyridinesulfonyl chloride, HCl)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes C
Risk Phrases 14-29-34
Safety Phrases 8-22-26-30-45-36/37/39
RIDADR UN 3265 8 / PGII
HS Code 2933399090

 Synthetic Route

~96%

chloro-3-pyridylsulfone Structure

chloro-3-pyridy...

CAS#:42899-76-3

Literature: Panchaud, Philippe; Renaud, Philippe Advanced Synthesis and Catalysis, 2004 , vol. 346, # 8 p. 925 - 928

~%

chloro-3-pyridylsulfone Structure

chloro-3-pyridy...

CAS#:42899-76-3

Literature: Pfizer Inc. Patent: US6124314 A1, 2000 ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Pyridinesulfonyl chloride
pyridine-3-sulfonyl chloride,hydrochloride
Pyridine-3-sulfonyl chloride hydrochloride
Pyridine-3-sulfonyl chloride
chloro-3-pyridylsulfone
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