Elaidamide
Elaidamide structure
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Common Name | Elaidamide | ||
|---|---|---|---|---|
| CAS Number | 4303-70-2 | Molecular Weight | 281.47700 | |
| Density | 0.879g/cm3 | Boiling Point | 433.3ºC at 760mmHg | |
| Molecular Formula | C18H35NO | Melting Point | 84-85ºC | |
| MSDS | N/A | Flash Point | 215.9ºC | |
Use of ElaidamideElaidamide is a fatty acid amide that has been found in the cerebrospinal fluid (CSF) of sleep-deprived cats. It inhibits rat microsomal epoxide hydrolase. Elaidamide also inhibits porcine pancreatic and human synovial phospholipase A2 (PLA2). In vivo, Elaidamide induces physiological sleep in rats. |
Summary: Elaidamide (trans-9-octadecenamide), with CAS number 4303-70-2, has a molecular formula of C18H35NO and a molecular weight of 281.48. Its melting point is 84-85°C, boiling point is 433.3°C at 760 mmHg, and density is 0.879 g/cm3. Elaidamide inhibits rat microsomal epoxide hydrolase and porcine pancreatic and human synovial phospholipase A2. Additionally, it induces physiological sleep in rats in vivo. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Elaidamide |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.879g/cm3 |
|---|---|
| Boiling Point | 433.3ºC at 760mmHg |
| Melting Point | 84-85ºC |
| Molecular Formula | C18H35NO |
| Molecular Weight | 281.47700 |
| Flash Point | 215.9ºC |
| Exact Mass | 281.27200 |
| PSA | 43.09000 |
| LogP | 6.20950 |
| InChIKey | FATBGEAMYMYZAF-MDZDMXLPSA-N |
| SMILES | CCCCCCCCC=CCCCCCCCC(N)=O |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2924199090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Elaidamide CAS#:4303-70-2 |
| Literature: Morisseau, Christophe; Newman, John W.; Dowdy, Deanna L.; Goodrow, Marvin H.; Hammock, Bruce D. Chemical Research in Toxicology, 2001 , vol. 14, # 4 p. 409 - 415 |
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Elaidamide CAS#:4303-70-2
Learn More
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| Literature: Novagali Pharma SA Patent: EP1746084 A1, 2007 ; Location in patent: Page/Page column 5 ; |
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Elaidamide CAS#:4303-70-2 |
| Literature: Divito, Erin B.; Davic, Andrew P.; Johnson, Mitchell E.; Cascio, Michael Analytical Chemistry, 2012 , vol. 84, # 5 p. 2388 - 2394 |
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Elaidamide CAS#:4303-70-2 |
| Literature: Rowney Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, 1855 , p. 532 |
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Elaidamide CAS#:4303-70-2 |
| Literature: Albitzki; Emeljanow Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1899 , vol. 31, p. 106 Chem. Zentralbl., 1899 , vol. 70, # I p. 1070 |
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Elaidamide CAS#:4303-70-2 |
| Literature: Kaufmann; Skiba Fette und Seifen, 1958 , vol. 60, p. 362 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Relative rate of fatty acid amide hydrolase hydrolysis of compound compared to that o...
Source: ChEMBL
Target: Fatty-acid amide hydrolase 1
External Id: CHEMBL683425
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| trans-9-Methyl-7-decenoic acid |
| trans-9-octadecenoylamide |
| 9-Methyldec-trans-7-enoic Acid |
| trans-oleamide |
| trans-9,10-octadecenoamide |
| elaidoyl amide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the Chinese name of 4303-70-2? |
| A: Chinese name of 4303-70-2 is 4303-70-2. |
| Q: What is the melting point of Elaidamide? |
| A: Melting point of Elaidamide is 84-85ºC. |
| Q: What is the molecular formula of Elaidamide? |
| A: Molecular formula of Elaidamide is C18H35NO. |
| Q: What is the LogP of Elaidamide? |
| A: LogP of Elaidamide is 6.20950. |
| Q: What is the CAS number of Elaidamide? |
| A: CAS number of Elaidamide is 4303-70-2. |
| Q: What is the English name of Elaidamide? |
| A: The English name of Elaidamide is Elaidamide. |
| Q: What is the SMILES notation of Elaidamide? |
| A: SMILES notation of Elaidamide is CCCCCCCCC=CCCCCCCCC(N)=O. |
| Q: What are the uses of Elaidamide? |
| A: Main uses of Elaidamide: Elaidamide is a fatty acid amide that has been found in the cerebrospinal fluid (CSF) of sleep-deprived cats. It inhibits rat microsomal epoxide hydrolase. Elaidamide also inhibits porcine pancreatic and human synovial phospholipase A2 (PLA2). In vivo, Elaidamide induces physiological sleep in rats. |
| Q: What is the InChIKey of Elaidamide? |
| A: InChIKey of Elaidamide is FATBGEAMYMYZAF-MDZDMXLPSA-N. |
| Q: What is the molecular weight of Elaidamide? |
| A: Molecular weight of Elaidamide is 281.47700. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |