431884-01-4

Modify Date: 2025-09-26 16:09:09

431884-01-4 Structure
431884-01-4 structure
Common Name 431884-01-4
CAS Number 431884-01-4 Molecular Weight 350.81
Density N/A Boiling Point N/A
Molecular Formula C19H15ClN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 431884-01-4


Antimalarial agent 13 (Compound 1) is a potent antimalarial agent. Antimalarial agent 13 shows inhibition with EC50 values of 124 nM and 2.5 μM against P. falciparum parasite and HepG2, respectively[1].

 Names

Name 431884-01-4

 431884-01-4 Biological Activity

Description Antimalarial agent 13 (Compound 1) is a potent antimalarial agent. Antimalarial agent 13 shows inhibition with EC50 values of 124 nM and 2.5 μM against P. falciparum parasite and HepG2, respectively[1].
Related Catalog
References

[1]. Gilson PR, et al. Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. J Med Chem. 2017 Feb 9;60(3):1171-1188.

 Chemical & Physical Properties

Molecular Formula C19H15ClN4O
Molecular Weight 350.81
InChIKey KLRNKMZSARWWTH-UHFFFAOYSA-N
SMILES Clc1cccc(Nc2nc(NCc3ccco3)c3ccccc3n2)c1
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