L-Tyrosine β-naphthylamide
L-Tyrosine β-naphthylamide structure
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Common Name | L-Tyrosine β-naphthylamide | ||
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| CAS Number | 4357-95-3 | Molecular Weight | 306.35800 | |
| Density | 1.296g/cm3 | Boiling Point | 610.3ºC at 760mmHg | |
| Molecular Formula | C19H18N2O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 322.9ºC | |
| Symbol |
GHS08 |
Signal Word | Warning | |
Use of L-Tyrosine β-naphthylamideL-Tyrosine β-naphthylamide is a tyrosine derivative[1]. |
Summary: h-tyr-betana (L-Tyrosine β-naphthylamide), CAS number 4357-95-3, molecular formula C19H18N2O2, molecular weight 306.36, for research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | h-tyr-betana |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | L-Tyrosine β-naphthylamide is a tyrosine derivative[1]. |
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| Related Catalog | |
| In Vitro | Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.296g/cm3 |
|---|---|
| Boiling Point | 610.3ºC at 760mmHg |
| Molecular Formula | C19H18N2O2 |
| Molecular Weight | 306.35800 |
| Flash Point | 322.9ºC |
| Exact Mass | 306.13700 |
| PSA | 75.35000 |
| LogP | 3.82720 |
| Index of Refraction | 1.715 |
| InChIKey | BZBYYTSHGRKCJJ-SFHVURJKSA-N |
| SMILES | NC(Cc1ccc(O)cc1)C(=O)Nc1ccc2ccccc2c1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn |
| Risk Phrases | 40 |
| Safety Phrases | 22-36 |
| RIDADR | NONH for all modes of transport |
This table lists relevant public references with title, journal and publication metadata for this compound.
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L-Tyrosine beta-naphthylamide is a potent competitive inhibitor of tyramine N-(hydroxycinnamoyl)transferase in vitro.
Phytochemistry 56 , 523-527, (2001) L-Tyrosine beta-naphthylamide, a synthetic substrate designed to measure tyrosine aminopeptidase activity, is a potent inhibitor of hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) ... |
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Membrane-bound tyrosine aminopeptidase activities in the rat brain throughout the estrous cycle.
Life Sci. 59 , 1097-1101, (1996) Puromycin sensitive and insensitive membrane-bound aminopeptidase activity levels during the estrous cycle in several brain areas have been described in this research. We have found the highest aminop... |
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Effect of lithium treatments on the tyrosine-aminopeptidase activities in the rat brain and the pituitary gland.
Arzneimittelforschung 49 , 816-819, (1999) Lithium (CAS 7439-93-2) is being utilized widely for the treatment of manic-depressive illness. However, the neurochemical mechanism of the ion action still remains relatively obscure. In the present ... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Einecs 224-432-6 |
| H-Tyr-bNA |
| TYROSINE-BETANA |
| L-tyrosine B-naphthylamide |
| L-Tyrosine--naphthylamide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the Chinese name of 4357-95-3? |
| A: Chinese name of 4357-95-3 is 4357-95-3. |
| Q: What is the safety information for h-tyr-betana? |
| A: Safety information for h-tyr-betana: 22-36. |
| Q: What is the English name of h-tyr-betana? |
| A: The English name of h-tyr-betana is h-tyr-betana. |
| Q: What is the CAS number of h-tyr-betana? |
| A: CAS number of h-tyr-betana is 4357-95-3. |
| Q: What is the boiling point of h-tyr-betana? |
| A: Boiling point of h-tyr-betana is 610.3ºC at 760mmHg. |
| Q: What is the polar surface area (PSA) of h-tyr-betana? |
| A: Polar surface area (PSA) of h-tyr-betana is 75.35000. |
| Q: What is the molecular formula of h-tyr-betana? |
| A: Molecular formula of h-tyr-betana is C19H18N2O2. |
| Q: What is the LogP of h-tyr-betana? |
| A: LogP of h-tyr-betana is 3.82720. |
| Q: What is the molecular weight of h-tyr-betana? |
| A: Molecular weight of h-tyr-betana is 306.35800. |
| Q: What is the InChIKey of h-tyr-betana? |
| A: InChIKey of h-tyr-betana is BZBYYTSHGRKCJJ-SFHVURJKSA-N. |