H-Thr(tBu)-OH

Modify Date: 2024-01-05 16:26:52

H-Thr(tBu)-OH Structure
H-Thr(tBu)-OH structure
Common Name H-Thr(tBu)-OH
CAS Number 4378-13-6 Molecular Weight 175.225
Density 1.1±0.1 g/cm3 Boiling Point 275.3±30.0 °C at 760 mmHg
Molecular Formula C8H17NO3 Melting Point 244-247ºC
MSDS Chinese USA Flash Point 120.3±24.6 °C

 Use of H-Thr(tBu)-OH


H-Thr(tBu)-OH is a threonine derivative[1].

 Names

Name O-tert-Butyl-L-threonine
Synonym More Synonyms

 H-Thr(tBu)-OH Biological Activity

Description H-Thr(tBu)-OH is a threonine derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 275.3±30.0 °C at 760 mmHg
Melting Point 244-247ºC
Molecular Formula C8H17NO3
Molecular Weight 175.225
Flash Point 120.3±24.6 °C
Exact Mass 175.120850
PSA 72.55000
LogP 1.22
Appearance of Characters Solid
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.464
Storage condition Store at RT.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922509090

 Synthetic Route

~97%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Chen, Chun-Chi; Rajagopal, Basker; Liu, Xuan Yu; Chen, Kuan Lin; Tyan, Yu-Chang; Lin, Fui; Lin, Po-Chiao Amino Acids, 2014 , vol. 46, # 2 p. 367 - 374

~85%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Hoeck, Stefan; Marti, Roger; Riedl, Rainer; Simeunovic, Marina Chimia, 2010 , vol. 64, # 3 p. 200 - 202

~%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Nakajima, Kiichiro; Neya, Masahiro; Yamada, Shinichi; Okawa, Kenji Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 9 p. 3049 - 3050

~%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Nakajima, Kiichiro; Neya, Masahiro; Yamada, Shinichi; Okawa, Kenji Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 9 p. 3049 - 3050

~%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Wuensch,E.; Jentsch,J. Chemische Berichte, 1964 , vol. 97, p. 2490 - 2496

~%

H-Thr(tBu)-OH Structure

H-Thr(tBu)-OH

CAS#:4378-13-6

Literature: Wang, Jidong; Okada, Yoshio; Li, Wei; Yokoi, Toshio; Zhu, Jintao Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 5 p. 621 - 624

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

O-T-BUTYL-D-THREONINE
H-D-Thr(tBu)-OH
H-Thr(tBu)-OH
O-tert.Butyl-D-threonine
O-(2-Methyl-2-propanyl)threonine
O-tert-Butyl-L-threonine
(2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid
L-Threonine, O-(1,1-dimethylethyl)-
Threonine, O-(1,1-dimethylethyl)-
(2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid
O-t-Butyl-L-threonine
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