4-Fluoro-2-methoxyphenol

Modify Date: 2025-11-04 16:01:47

4-Fluoro-2-methoxyphenol Structure
4-Fluoro-2-methoxyphenol structure
Common Name 4-Fluoro-2-methoxyphenol
CAS Number 450-93-1 Molecular Weight 142.128
Density 1.2±0.1 g/cm3 Boiling Point 201.9±20.0 °C at 760 mmHg
Molecular Formula C7H7FO2 Melting Point N/A
MSDS Chinese USA Flash Point 101.4±18.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Fluoro-2-methoxyphenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 201.9±20.0 °C at 760 mmHg
Molecular Formula C7H7FO2
Molecular Weight 142.128
Flash Point 101.4±18.3 °C
Exact Mass 142.043015
PSA 29.46000
LogP 1.52
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.512
InChIKey OULGLTLTWBZBLO-UHFFFAOYSA-N
SMILES COc1cc(F)ccc1O

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR 2735
WGK Germany 3
HS Code 2909500000

 Synthetic Route

~86%

4-Fluoro-2-methoxyphenol Structure

4-Fluoro-2-meth...

CAS#:450-93-1

Literature: Sanz, Roberto; Martinez, Alberto; Marcos, Cesar; Fananas, Francisco J. Synlett, 2008 , # 13 p. 1957 - 1960

~68%

4-Fluoro-2-methoxyphenol Structure

4-Fluoro-2-meth...

CAS#:450-93-1

Literature: Mewshaw, Richard E.; Zhou, Dahui; Zhou, Ping; Shi, Xiaojie; Hornby, Geoffrey; Spangler, Taylor; Scerni, Rosemary; Smith, Deborah; Schechter, Lee E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3823 - 3842

~%

4-Fluoro-2-methoxyphenol Structure

4-Fluoro-2-meth...

CAS#:450-93-1

Literature: Mewshaw, Richard E.; Zhou, Dahui; Zhou, Ping; Shi, Xiaojie; Hornby, Geoffrey; Spangler, Taylor; Scerni, Rosemary; Smith, Deborah; Schechter, Lee E.; Andree, Terrance H. Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3823 - 3842

 Customs

HS Code 2909500000
Summary 2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles5

More Articles
Oxidation of substituted 4-fluorobenzaldehydes: application to the no-carrier-added syntheses of 4-[18F]fluoroguaiacol and 4-[18F]fluorocatechol.

Int. J. Rad. Appl. Instrum. A. 42(7) , 673-81, (1991)

The synthesis of 4-[18F]fluoroguaiacol (4-[18F]fluoro-2-methoxyphenol) has been achieved in no-carrier-added form starting from 2-methoxy-4-nitrobenzaldehyde, using nucleophilic aromatic substitution ...

4-fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis.

Eur. J. Pharmacol. 660(2-3) , 445-53, (2011)

Apocynin, a methoxy-substituted catechol (4-hydroxy-3-methoxyacetophenone), originally extracted from the roots of Picrorhiza kurroa, has been extensively used as a non-toxic inhibitor of the multienz...

Diels-Alder reactions of halogenated masked o-benzoquinones: synthesis of halogen-substituted bicyclo [2.2. 2] octenones.

Tetrahedron Lett. 50(7) , 773-775, (2009)

 Synonyms

MFCD00070797
4-Fluoro-2-methyoxyphenol
Phenol,4-fluoro-2-methoxy
4-fluoroguaiacol
Phenol, 4-fluoro-2-methoxy-
2-Methoxy-4-fluorophenol
3-methoxy-4-hydroxyfluorobenzene
4-Fluoro-2-methoxyphenol
4-fluoro-2-methoxy-phenol
5-Fluoro-2-hydroxyanisole
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