Glyhexamide

Modify Date: 2025-08-27 15:08:29

Glyhexamide Structure
Glyhexamide structure
Common Name Glyhexamide
CAS Number 451-71-8 Molecular Weight 322.42200
Density 1.3g/cm3 Boiling Point N/A
Molecular Formula C16H22N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glyhexamide


Glyhexamide is an effective hypoglycemic agent in adult diabetics.

 Names

Name 1-cyclohexyl-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)urea
Synonym More Synonyms

 Glyhexamide Biological Activity

Description Glyhexamide is an effective hypoglycemic agent in adult diabetics.
Related Catalog
In Vivo Glyhexamide, a new cyclic sulfonylurea, is an effective hypoglycemic agent in adult diabetics, this activity is unaccompanied by increases in serum (immunoreactive) insulin concentrations.
References

[1]. E. M. Gold, et al. Insulin Production in Overt (Maturity-Onset) Diabetes: Absence of Hyperinsulinemia Despite Hyperglycemia Induced by Contraceptive Steroids. Metabolic Effects of Gonadal Hormones and Contraceptive Steroids pp 144-156.

 Chemical & Physical Properties

Density 1.3g/cm3
Molecular Formula C16H22N2O3S
Molecular Weight 322.42200
Exact Mass 322.13500
PSA 83.65000
LogP 4.35850
Index of Refraction 1.602
InChIKey NFRPNQDSKJJQGV-UHFFFAOYSA-N
SMILES O=C(NC1CCCCC1)NS(=O)(=O)c1ccc2c(c1)CCC2
Storage condition 2-8℃

 Safety Information

HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 GlyhexamideBioassay

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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Bas...
Source: Broad Institute
Target: N/A
External Id: 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Prima...
Source: NCGC
Target: apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7]
External Id: AMA1100
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: abhydrolase domain-containing protein 4 isoform 1 [Mus musculus]
External Id: ABHD4_INH_FP_1536_1X%INH PRUN
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 Synonyms

HZ 21
Subose
SQ 15,860
GLYHEXAMIDE
Serbose
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