2-Propanol,1-chloro-3-fluoro-

Modify Date: 2024-02-01 16:12:43

2-Propanol,1-chloro-3-fluoro- Structure
2-Propanol,1-chloro-3-fluoro- structure
Common Name 2-Propanol,1-chloro-3-fluoro-
CAS Number 453-11-2 Molecular Weight 112.53100
Density 1.3 Boiling Point 158.1ºC at 760mmHg
Molecular Formula C3H6ClFO Melting Point N/A
MSDS N/A Flash Point 49.4ºC

 Names

Name 1-chloro-3-fluoroisopropanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3
Boiling Point 158.1ºC at 760mmHg
Molecular Formula C3H6ClFO
Molecular Weight 112.53100
Flash Point 49.4ºC
Exact Mass 112.00900
PSA 20.23000
LogP 0.55560
Vapour Pressure 0.951mmHg at 25°C
Index of Refraction 1.438

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1-Chloro-3-fluoroisopropanol
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H331:Toxic if inhaled
H302:Harmful if swallowed
H312:Harmful in contact with skin
H226:Flammable liquid and vapour
Keep away from heat/sparks/open flames/hot surfaces. No smoking
P210:
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P280:Wear protective gloves/protective clothing/eye protection/face protection
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with
water/shower
P405:Store locked up

Section3. Composition/information on ingredients.
Ingredient name:1-Chloro-3-fluoroisopropanol
CAS number:453-11-2

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C3H6ClFO
Molecular weight: 112.5

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen chloride, hydrogen fluoride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN1992Class: 3Packing group: III
Proper shipping name: FLAMMABLE LIQUIDS, TOXIC, N.O.S. (1-Chloro-3-fluoroisopropanol)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA9000000
CHEMICAL NAME :
2-Propanol, 1-chloro-3-fluoro-
CAS REGISTRY NUMBER :
453-11-2
BEILSTEIN REFERENCE NO. :
1732051
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H6-Cl-F-O
MOLECULAR WEIGHT :
112.54
WISWESSER LINE NOTATION :
G1YQ1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00320

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R10;R20/21/22
Safety Phrases S23-S36/37
RIDADR UN 2929
Packaging Group III

 Synonyms

1-chloro-3-fluoro-propan-2-ol
1-chloro-3-fluoro-2-propano
chloro-1 fluoro-3 propanol-2
2-propanol,1-chloro-3-fluoro
MFCD00045284
1-fluoro-3-chloro-isopropanol
1-Chlor-3-fluor-propan-2-ol
1-Chloro-3-fluoro-2-propanol