ci 50206
Modify Date: 2024-01-08 18:39:48
ci 50206 structure
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Common Name | ci 50206 | ||
|---|---|---|---|---|
| CAS Number | 4569-86-2 | Molecular Weight | 378.89800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23ClN4 | Melting Point | 285 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of ci 50206Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy)[1][2]. |
| Name | 2-N,2-N-diethyl-10-phenylphenazin-10-ium-2,8-diamine,chloride |
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| Synonym | More Synonyms |
| Description | Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy)[1][2]. |
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| Related Catalog | |
| Target |
Acetylcholinesterase:1.58 μM (Ki) Butyrylcholinesterase:0.51 μM (Ki) |
| In Vitro | Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell[1].Methylene Violet 3RAX (0-400 µM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM[1]. |
| References |
| Melting Point | 285 °C (dec.)(lit.) |
|---|---|
| Molecular Formula | C22H23ClN4 |
| Molecular Weight | 378.89800 |
| Exact Mass | 378.16100 |
| PSA | 46.03000 |
| LogP | 1.67830 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Supravital staining of mitochondria with phenosafranin dyes.
Biochim. Biophys. Acta 11 , 480, (1953)
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| Methylene violet 3RAX |
| 3-amino-7-N,N-diethylamino-2-methyl-5-phenyl-phenazinium chloride |
| MFCD00013433 |
| 3-amino-7-diethylamino-5-phenyl-phenazinium,chloride |
| methylene violet |
| N,N-Diethylphenosafranine |
| 3-Amino-7-diaethylamino-5-phenyl-phenazinium,Chlorid |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: ci 50206
- Price: ￥648.0/5g ￥188.0/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: CI 50206
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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