1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea
1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea structure
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Common Name | 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea | ||
|---|---|---|---|---|
| CAS Number | 457-82-9 | Molecular Weight | 253.31900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H8FN3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C10H8FN3S2 |
|---|---|
| Molecular Weight | 253.31900 |
| Exact Mass | 253.01400 |
| PSA | 104.32000 |
| LogP | 3.38460 |
| InChIKey | ZFAMDCCGNXBKRF-UHFFFAOYSA-N |
| SMILES | Fc1ccc(NC(=S)Nc2nccs2)cc1 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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1-(4-fluorophen... CAS#:457-82-9 |
| Literature: Buu-Hoi et al. Journal of the Chemical Society, 1955 , p. 1581,1583 Errata, 1957 |
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1-(4-fluorophen... CAS#:457-82-9 |
| Literature: Buu-Hoi et al. Journal of the Chemical Society, 1955 , p. 1581,1583 Errata, 1957 |
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1-(4-fluorophen... CAS#:457-82-9 |
| Literature: Buu-Hoi et al. Journal of the Chemical Society, 1955 , p. 1581,1583 Errata, 1957 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
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| DownStream 0 | |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Single concentration confirmation of small molecule activators of the apoptotic arm o...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A406-UPR-CHOP-CP-Agonist-Assay
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Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| hms2694h04 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: The English name of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea. |
| Q: What is the Chinese name of 457-82-9? |
| A: Chinese name of 457-82-9 is 457-82-9. |
| Q: What is the molecular formula of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: Molecular formula of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is C10H8FN3S2. |
| Q: What is the InChIKey of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: InChIKey of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is ZFAMDCCGNXBKRF-UHFFFAOYSA-N. |
| Q: What are the upstream materials of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: Related upstream materials(CAS) of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea: 371-40-4;404-52-4;96-50-4;1544-68-9. |
| Q: What is the CAS number of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: CAS number of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is 457-82-9. |
| Q: What is the polar surface area (PSA) of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: Polar surface area (PSA) of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is 104.32000. |
| Q: What is the SMILES notation of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: SMILES notation of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is Fc1ccc(NC(=S)Nc2nccs2)cc1. |
| Q: What is the LogP of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea? |
| A: LogP of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea is 3.38460. |
| Q: What English synonyms does 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea have? |
| A: English synonyms of 1-(4-fluorophenyl)-3-(1,3-thiazol-2-yl)thiourea: hms2694h04. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |