(S) 93-31
Modify Date: 2024-01-14 16:48:02
(S) 93-31 structure
|
Common Name | (S) 93-31 | ||
|---|---|---|---|---|
| CAS Number | 457897-98-2 | Molecular Weight | 489.452 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H30Cl2N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (S) 93-31A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM); maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions. |
| Name | (S) 93-31 |
|---|
| Description | A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM); maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions. |
|---|---|
| References | References 1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318. View Related Products by Target iGluR |
| Molecular Formula | C22H30Cl2N2O4S |
|---|---|
| Molecular Weight | 489.452 |