- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: (S) 93-31
- Price: ￥Inquiry/25mg ￥Inquiry/100mg ￥Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: (S) 93-31
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- DC Chemicals Limited
- China
- Product Name: (S) 93-31
- Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
457897-98-2
457897-98-2 structure
- Name: (S) 93-31
- Chemical Name: (S) 93-31
- CAS Number: 457897-98-2
- Molecular Formula: C22H30Cl2N2O4S
- Molecular Weight: 489.452
- Create Date: 2020-01-11 08:53:52
- Modify Date: 2024-01-14 16:48:02
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A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM); maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions.
| Name | (S) 93-31 |
|---|
| Description | A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM); maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions. |
|---|---|
| References | References 1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318. View Related Products by Target iGluR |
| Molecular Formula | C22H30Cl2N2O4S |
|---|---|
| Molecular Weight | 489.452 |