1-acetylaziridine

Modify Date: 2024-01-08 13:45:46

1-acetylaziridine Structure
1-acetylaziridine structure
Common Name 1-acetylaziridine
CAS Number 460-07-1 Molecular Weight 85.10450
Density 1.126g/cm3 Boiling Point 174.2ºC at 760mmHg
Molecular Formula C4H7NO Melting Point N/A
MSDS N/A Flash Point 76.2ºC

 Names

Name 1-(aziridin-1-yl)ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.126g/cm3
Boiling Point 174.2ºC at 760mmHg
Molecular Formula C4H7NO
Molecular Weight 85.10450
Flash Point 76.2ºC
Exact Mass 85.05280
PSA 20.08000
Vapour Pressure 1.22mmHg at 25°C
Index of Refraction 1.494

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CM6300000
CHEMICAL NAME :
Aziridine, 1-acetyl-
CAS REGISTRY NUMBER :
460-07-1
BEILSTEIN REFERENCE NO. :
0105879
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H7-N-O
MOLECULAR WEIGHT :
85.12
WISWESSER LINE NOTATION :
T3NTJ AV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
78 mg/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg/33W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
80 mg/kg/16W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954

 Safety Information

HS Code 2933990090

 Synthetic Route

~%

1-acetylaziridine Structure

1-acetylaziridine

CAS#:460-07-1

Literature: Gilead Sciences, Inc. Patent: US5952375 A1, 1999 ;

~%

1-acetylaziridine Structure

1-acetylaziridine

CAS#:460-07-1

Literature: Bestian Justus Liebigs Annalen der Chemie, 1950 , vol. 566, p. 210,231

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-Acetylaziridine
N-acetyl aziridine
Acetylethylenimide
N-Acetylethyleneimine
AZIRIDINE,1-ACETYL
1-Acetyl-aziridin
Acetylethylenimine
EINECS 207-301-8
N-Acetylethylenimine
Acetylethyleneimine
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