4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile

Modify Date: 2024-01-14 19:14:11

4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile Structure
4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile structure
Common Name 4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile
CAS Number 460746-48-9 Molecular Weight 263.29100
Density 1.27g/cm3 Boiling Point 475.6ºC at 760 mmHg
Molecular Formula C17H13NO2 Melting Point N/A
MSDS N/A Flash Point 241.5ºC

 Names

Name 4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 475.6ºC at 760 mmHg
Molecular Formula C17H13NO2
Molecular Weight 263.29100
Flash Point 241.5ºC
Exact Mass 263.09500
PSA 57.16000
LogP 3.50628
Index of Refraction 1.669

 Synthetic Route

~95%

4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile Structure

4-[2-(2-hydroxy...

CAS#:460746-48-9

Literature: Cowart, Marlon; Faghih, Ramin; Curtis, Michael P.; Gfesser, Gregory A.; Bennani, Youssef L.; Black, Lawrence A.; Pan, Liping; Marsh, Kennan C.; Sullivan, James P.; Esbenshade, Timothy A.; Fox, Gerard B.; Hancock, Arthur A. Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 38 - 55

~72%

4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile Structure

4-[2-(2-hydroxy...

CAS#:460746-48-9

Literature: Cowart, Marlon D.; Pu, Yu-Ming; Ku, Yi-Yin; Grieme, Timothy A.; Gupta, Ashok K.; Plata, Daniel J.; Faghih, Ramin; Gfesser, Gregory A. Patent: US2004/54185 A1, 2004 ; Location in patent: Page 12 ; US 20040054185 A1

~%

4-[2-(2-hydroxyethyl)-1-benzofuran-5-yl]benzonitrile Structure

4-[2-(2-hydroxy...

CAS#:460746-48-9

Literature: Cowart, Marlon; Faghih, Ramin; Curtis, Michael P.; Gfesser, Gregory A.; Bennani, Youssef L.; Black, Lawrence A.; Pan, Liping; Marsh, Kennan C.; Sullivan, James P.; Esbenshade, Timothy A.; Fox, Gerard B.; Hancock, Arthur A. Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 38 - 55