Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate

Modify Date: 2025-08-21 14:44:45

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure
Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate structure
Common Name Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate
CAS Number 46193-76-4 Molecular Weight 195.238
Density 1.3±0.1 g/cm3 Boiling Point 345.7±22.0 °C at 760 mmHg
Molecular Formula C9H9NO2S Melting Point 131-132ºC
MSDS N/A Flash Point 162.9±22.3 °C

 Names

Name Ethyl 4H-Thieno[2,3-d]Pyrrole-5-Carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 345.7±22.0 °C at 760 mmHg
Melting Point 131-132ºC
Molecular Formula C9H9NO2S
Molecular Weight 195.238
Flash Point 162.9±22.3 °C
Exact Mass 195.035400
PSA 70.33000
LogP 4.03
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.652
InChIKey BLUDZFMRKHHPGZ-UHFFFAOYSA-N
SMILES CCOC(=O)c1cc2sccc2[nH]1

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~50%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: Jiang, Xin-Dong; Zhang, Houjun; Zhang, Yuanlin; Zhao, Weili Tetrahedron, 2012 , vol. 68, # 47 p. 9795 - 9801,7

~66%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: AstraZeneca UK Limited Patent: US6479527 B1, 2002 ; US 6479527 B1

~93%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: Wu, Yayang; Cheng, Chi; Jiao, Lijuan; Yu, Changjiang; Wang, Sufan; Wei, Yun; Mu, Xiaolong; Hao, Erhong Organic Letters, 2014 , vol. 16, # 3 p. 748 - 751

~%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298

~%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: GLAXO GROUP LIMITED; BLUNT, Richard; EATHERTON, Andrew John; GARZYA, Vincenzo; HEALY, Mark Patrick; MYATT, James; PORTER, Roderick Alan Patent: WO2011/12622 A1, 2011 ; Location in patent: Page/Page column 103; 104 ; WO 2011/012622 A1

~%

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate Structure

Ethyl 4H-thieno...

CAS#:46193-76-4

Literature: Soth,S. et al. Canadian Journal of Chemistry, 1978 , vol. 56, p. 1429 - 1434

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

View more

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: ORF 73 [Human herpesvirus 8 type M]
External Id: HMS791
Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600
Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Alphascreen assay for small molecules abrogating mHTT-CaM Interaction
Source: 24983
Target: Huntingtin
External Id: KUHTS-Muma KU-CaM-Htt INH-01
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
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 Synonyms

Ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate
4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, ethyl ester
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