SLLK, Control Peptide for TSP1 Inhibitor
Modify Date: 2025-08-26 19:10:50
SLLK, Control Peptide for TSP1 Inhibitor structure
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Common Name | SLLK, Control Peptide for TSP1 Inhibitor | ||
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| CAS Number | 464924-27-4 | Molecular Weight | 459.580 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 690.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H41N5O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 371.2±34.3 °C | |
Use of SLLK, Control Peptide for TSP1 InhibitorSLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). |
| Name | (2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-1,3-dihydroxy-propylidene]amino]-1-hydroxy-4-methyl-pentylidene]amino]-1-hydroxy-4-methyl-pentylidene]amino]hexanoic acid |
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| Description | SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). |
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| Related Catalog | |
| In Vivo | TGF-β1 is significantly lower (0.10±0.01 pg/mL) in the plasma of mice receiving LSKL compared with that in plasma of mice receiving SLLK control peptide at day 42 (0.20±0.02 pg/mL; P=0.0001). mRNA expression is assessed in the suprarenal aortic lysates obtained from mice receiving SLLK and LSKL peptides[1]. Akita mice treated with 30 mg/kg LSKL have significantly increased nephrin expression, greater than twofold, compared with renal lysates from either saline controls or SLLK-treated mice[2]. |
| Animal Admin | Sterile solutions of LSKL or SLLK peptide are made in stock solutions of 3.0 mg/mL (high dose) or 0.3 mg/mL (low dose) in sterile saline. The i.p. injection of LSKL, SLLK, or saline began 2 weeks after uninephrectomy and continues thrice weekly for 15 weeks. For the low-dosage treatment regimen, each group of 20 mice receives 3 mg/kg body weight of peptide (LSKL or SLLK) per injection or saline (100 μL/10 g body weight per injection). For the high-dosage treatment regimen, Akita mice ae given i.p. injections of LSKL or SLLK peptide at 30 mg/kg body weight per injection or saline (100 μL/10 g body weight per injection). |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 690.1±65.0 °C at 760 mmHg |
| Molecular Formula | C21H41N5O6 |
| Molecular Weight | 459.580 |
| Flash Point | 371.2±34.3 °C |
| Exact Mass | 459.305695 |
| LogP | 2.91 |
| Vapour Pressure | 0.0±4.9 mmHg at 25°C |
| Index of Refraction | 1.565 |
| Storage condition | 2-8℃ |