Grayanotoxin II

Modify Date: 2024-02-04 20:39:43

Grayanotoxin II Structure
Grayanotoxin II structure
Common Name Grayanotoxin II
CAS Number 4678-44-8 Molecular Weight 352.46500
Density 1.3g/cm3 Boiling Point 522.9ºC at 760 mmHg
Molecular Formula C20H32O5 Melting Point N/A
MSDS N/A Flash Point 237.9ºC

 Use of Grayanotoxin II


Grayanotoxin II is a potent analgesic agent, is a diterpenoid. Grayanotoxin II shows significant analgesic activity[1].

 Names

Name (3β,6β,14R)-Grayanotox-10-ene-3,5,6,14,16-pentol
Synonym More Synonyms

 Grayanotoxin II Biological Activity

Description Grayanotoxin II is a potent analgesic agent, is a diterpenoid. Grayanotoxin II shows significant analgesic activity[1].
Related Catalog
In Vivo Grayanotoxin II (5 mg/kg; i.p.) 在乙酸诱导的小鼠扭体试验中显示出显着的镇痛活性[1]。 Animal Model: Kunming mice (acetic acid-induced writhing test)[1] Dosage: 5 mg/kg Administration: I.p. Result: Showed significant analgesic activity in mice.
References

[1]. Chang-Shan Niu, et al. Analgesic diterpenoids from the twigs of Pieris formosa. Tetrahedron. 2016, 72(1): 44-49.

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 522.9ºC at 760 mmHg
Molecular Formula C20H32O5
Molecular Weight 352.46500
Flash Point 237.9ºC
Exact Mass 352.22500
PSA 101.15000
LogP 0.97350
Index of Refraction 1.61

 Safety Information

RIDADR UN 3172
Hazard Class 6.1(a)

 Synonyms

7-(prop-2-in-1-yloxy)-1-benzopyran-2-one
7-Propargyloxy-cumarin [German]
2H-1-Benzopyran-2-one,7-(2-propynyloxy)
(7R)-1,1,8-Trimethyl-4-methylen-(3ac,4at)-dodecahydro-7r,9ac-methano-cyclopenta[b]heptalen-2t,8c,11t,11at,12anti-pentaol
Grayanatoxin-II
Grayanotoxin-II
(3aR)-2c.8t.11c.11ac.12anti-Pentahydroxy-1.1.8c-trimethyl-4-methylen-(3arH.4acH)-tetradecahydro-7t.9at-methano-cyclopenta[b]heptalen
Andromedenol
(7-coumaryloxy)methylacetylene
(7R)-1,1,8-trimethyl-4-methylene-(3ac,4at)-dodecahydro-7r,9ac-methano-cyclopenta[b]heptalene-2t,8c,11t,11at,12anti-pentaol
(7-propargyloxy)coumarin
7-Propargyloxy-cumarin
7-(2-Propynyloxy)-2H-1-benzopyran-2-one
7-(prop-2-yn-1-yloxy)-2H-chromen-2-one