AFP464
Modify Date: 2024-01-09 19:01:29
AFP464 structure
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Common Name | AFP464 | ||
|---|---|---|---|---|
| CAS Number | 468719-52-0 | Molecular Weight | 448.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23F3N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AFP464AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator. |
| Name | (2S)-2,6-diamino-N-[4-(5-amino-6,8-difluoro-7-methyl-4-oxochromen-2-yl)-2-fluorophenyl]hexanamide |
|---|---|
| Synonym | More Synonyms |
| Description | AFP464, is an active HIF-1α inhibitor with an IC50 of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator. |
|---|---|
| Related Catalog | |
| Target |
IC50：0.25 μM (HIF-1α)[1] |
| References |
| Molecular Formula | C22H23F3N4O3 |
|---|---|
| Molecular Weight | 448.44 |
| PSA | 203.61000 |
| LogP | 6.37880 |
| AFP-464 free base |
| Hexanamide,2,6-diamino-N-(4-(5-amino-6,8-difluoro-7-methyl-4-oxo-4H-1-benzopyran-2-yl)-2-fluorophenyl)-,(2S) |
| UNII-O3HFV0VQ36 |