DPPC-d71

Modify Date: 2024-04-09 16:01:44

DPPC-d71 Structure
DPPC-d71 structure
Common Name DPPC-d71
CAS Number 474943-49-2 Molecular Weight 805.48
Density N/A Boiling Point N/A
Molecular Formula C40H9D71NO8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPPC-d71


DPPC-d71 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in

 Names

Name DPPC-d71

 DPPC-d71 Biological Activity

Description DPPC-d71 is deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References

[1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.

[2]. Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67(12):1197-201.

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C40H9D71NO8P
Molecular Weight 805.48