Colfosceril palmitate

Modify Date: 2025-08-21 06:14:24

Colfosceril palmitate Structure
Colfosceril palmitate structure
 Common Name Colfosceril palmitate
CAS Number 63-89-8 Molecular Weight 734.039
Density N/A Boiling Point N/A
Molecular Formula C40H80NO8P Melting Point 229-229.5 °C
MSDS Chinese USA Flash Point N/A

 Use of Colfosceril palmitate


DPPC is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers.

 Names

Name 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
Synonym More Synonyms

 Colfosceril palmitate Biological Activity

Description DPPC is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.

 Chemical & Physical Properties

Melting Point 229-229.5 °C
Molecular Formula C40H80NO8P
Molecular Weight 734.039
Exact Mass 733.562134
PSA 121.00000
LogP 10.88
InChIKey KILNVBDSWZSGLL-KXQOOQHDSA-N
SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC
Storage condition −20°C
Stability Stable. Incompatible with strong oxidizing agents.

 Safety Information

Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles91

More Articles
Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.

Int. J. Pharm. 473(1-2) , 334-44, (2014)

CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the ne...

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m...

 Colfosceril palmitateBioassay

View more

Name: Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit alpha-1
External Id: CHEMBL5291800
Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Binding affinity towards human ESR1 in an in vitro cell free assay (CRO assay) measur...
Source: ChEMBL
Target: Estrogen receptor
External Id: CHEMBL5291792
Name: Compound was evaluated for inhibition of human F2 in an in vitro cell free assay meas...
Source: ChEMBL
Target: Prothrombin
External Id: CHEMBL5291794
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Binding affinity towards human DRD1 in an in vitro assay with cellular components (NI...
Source: ChEMBL
Target: D(1A) dopamine receptor
External Id: CHEMBL5291779
Name: Binding affinity towards human DRD3 in an in vitro assay with cellular components mea...
Source: ChEMBL
Target: D(3) dopamine receptor
External Id: CHEMBL5291782
Name: A screen for small molecules that modulate mitochondrial supercomplex formation
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1482
Name: qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr...
Source: 824
Target: N/A
External Id: SPEC167MG
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 Synonyms

1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine
1,2-Dipalmitoyl-L-3-phosphatidylcholine
Colfosceril palmitate
L-α-DPPC
1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium Inner Salt 4-Oxide
(2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
1,2-Dipalmitoyl-sn-3-glycerophosphocholine
b,g-Dipalmitoyl L-α-phosphatidylcholine
MFCD00036903
1,2-Dipalmitoyl-3-sn-phosphatidylcholine
Ethanaminium, 2-[[[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine
L-b,g-Dipalmitoyl-α-lecithin
1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine
DPPC
L-α-Dipalmitoyllecithin
1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylcholine
1,2-Dipalmitoyl-L-α-lecithin
129Y83
1,2-Dipalmitoylglycero-3-phosphocholine
L-DPPC
L-Dipalmitoyl Lecithin
EINECS 232-642-4
(2R)-2,3-Bis(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
L-α-Dipalmitoylphosphatidylcholine
Colfosceril
1,2-dipalmitoyl-sn-glycero-3-Phosphatidylcholine
1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine
sn-3-Dipalmitoyllecithin
b,g-Dipalmitoyl L-a-Phosphatidylcholine
L-α-Dipalmitoylecithin
1,2-Dipalmitoyl-L-α-phosphatidylcholine
L-a-DPPC
L-b,g-Dipalmitoyl-α-phosphatidylcholine
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