3'-Hydroxypterostilbene

Modify Date: 2024-01-10 20:54:58

3'-Hydroxypterostilbene structure	Common Name	3'-Hydroxypterostilbene
	CAS Number	475231-21-1	Molecular Weight	272.296
	Density	1.3±0.1 g/cm3	Boiling Point	469.7±45.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	237.8±28.7 °C

Use of 3'-Hydroxypterostilbene

3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

Name	3'-Hydroxypterostilbene
Synonym	More Synonyms

Description	3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
Target	Apoptosis[1] Autophagy[1]
References	[1]. Cheng TC, et al. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. PLoS One. 2014 Nov 12;9(11):e111814.

Density	1.3±0.1 g/cm3
Boiling Point	469.7±45.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₆O₄
Molecular Weight	272.296
Flash Point	237.8±28.7 °C
Exact Mass	272.104858
PSA	58.92000
LogP	3.68
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.665
Storage condition	-20℃