6-methylpiperidin-2-one

Modify Date: 2024-01-11 17:41:02

6-methylpiperidin-2-one Structure
6-methylpiperidin-2-one structure
Common Name 6-methylpiperidin-2-one
CAS Number 4775-98-8 Molecular Weight 113.15800
Density 0.951g/cm3 Boiling Point 254ºC at 760mmHg
Molecular Formula C6H11NO Melting Point N/A
MSDS N/A Flash Point 138.6ºC

 Names

Name 6-methylpiperidin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.951g/cm3
Boiling Point 254ºC at 760mmHg
Molecular Formula C6H11NO
Molecular Weight 113.15800
Flash Point 138.6ºC
Exact Mass 113.08400
PSA 32.59000
LogP 0.95090
Index of Refraction 1.438

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TO0125000
CHEMICAL NAME :
2-Piperidone, 6-methyl-
CAS REGISTRY NUMBER :
4775-98-8
LAST UPDATED :
199203
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H11-N-O
MOLECULAR WEIGHT :
113.18
WISWESSER LINE NOTATION :
T6NVTJ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
2300 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - muscle weakness Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903

 Synthetic Route

 Synonyms

EINECS 225-321-5
6-Methyl-2-piperidone
2-PIPERIDONE,6-METHYL
6-methylpiperid-2-one
Methylpentanonisoxim
6-methyl-2-oxo-3,4,5,6-tetrahydropyridine
2-Piperidinone,6-methyl
Methylpentanonisoxim [German]
(+/-)-6-methyl-2-piperidinone
Methylpentanone isoxime