2'-Deoxyuridine-1′-13C

Modify Date: 2024-01-09 15:02:47

2'-Deoxyuridine-1′-13C Structure
2'-Deoxyuridine-1′-13C structure
Common Name 2'-Deoxyuridine-1′-13C
CAS Number 478510-85-9 Molecular Weight 229.19500
Density N/A Boiling Point N/A
Molecular Formula C9H12N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Deoxyuridine-1′-13C


2'-Deoxyuridine-1′-13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

 Names

Name [1'-13c]2'-deoxyuridine
Synonym More Synonyms

 2'-Deoxyuridine-1′-13C Biological Activity

Description 2'-Deoxyuridine-1′-13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.

 Chemical & Physical Properties

Molecular Formula C9H12N2O5
Molecular Weight 229.19500
Exact Mass 229.07800
PSA 104.55000

 Synonyms

2'-Deoxyuridine-1`-13C