N-Hydroxypiperidine

Modify Date: 2026-07-01 11:00:30

N-Hydroxypiperidine Structure
N-Hydroxypiperidine structure
Common Name N-Hydroxypiperidine
CAS Number 4801-58-5 Molecular Weight 101.14700
Density 1.07g/cm3 Boiling Point 175.7ºC at 760 mmHg
Molecular Formula C5H11NO Melting Point 37-39ºC
MSDS Chinese USA Flash Point 78ºC

 Names

Name 1-Hydroxypiperidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.07g/cm3
Boiling Point 175.7ºC at 760 mmHg
Melting Point 37-39ºC
Molecular Formula C5H11NO
Molecular Weight 101.14700
Flash Point 78ºC
Exact Mass 101.08400
PSA 23.47000
LogP 0.79940
Index of Refraction 1.508
InChIKey LKPFBGKZCCBZDK-UHFFFAOYSA-N
SMILES ON1CCCCC1
Storage condition 2~8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN6829550
CHEMICAL NAME :
1-Piperidinol
CAS REGISTRY NUMBER :
4801-58-5
BEILSTEIN REFERENCE NO. :
0102726
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H11-N-O
MOLECULAR WEIGHT :
101.17
WISWESSER LINE NOTATION :
T6NTJ AQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#05185

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3.0
RTECS TN6829550
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles3

More Articles
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.

PLoS ONE 7(12) , e52790, (2012)

Latent M. tuberculosis infection presents one of the major obstacles in the global eradication of tuberculosis (TB). Cholesterol plays a critical role in the persistence of M. tuberculosis within the ...

Biological N-oxidation of piperidine in vitro.

Zhongguo Yao Li Xue Bao 10(3) , 252-6, (1989)

The biological N-oxidation of piperidine, a pharmacologically active biogenic amine of mammals and human beings, was studied in vitro. After incubation of piperidine-HCl in a fortified rat liver micro...

On the effect of thalidomide on Mycobacterium avium subspecies paratuberculosis in culture.

Int. J. Infect. Dis. 13(5) , e254-63, (2009)

Without known mechanisms of action, thalidomide is used to treat a variety of non-malignant 'idiopathic' diseases. There is increasing concern that Mycobacterium avium subspecies paratuberculosis (MAP...

 N-HydroxypiperidineBioassay

View more

Name: Compound was evaluated for ability to enhance the binding of (+/-)-[3H]nicotine to th...
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL634005
Name: Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at ...
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL632853
Name: Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at ...
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL636099
Name: Maximum percent of enhancement of binding.
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL874428
Name: Maximum percent of inhibition of binding was determined
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL633999
Name: Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a d...
Source: ChEMBL
Target: Neuronal acetylcholine receptor subunit alpha-7
External Id: CHEMBL638617
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 Synonyms

1-HYDROXYPIPERIDINE
EINECS 225-362-9
MFCD00038048
Piperidin-1-ol
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