Osthenol
Modify Date: 2024-01-06 18:07:00
Osthenol structure
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Common Name | Osthenol | ||
|---|---|---|---|---|
| CAS Number | 484-14-0 | Molecular Weight | 230.25900 | |
| Density | 1.203g/cm3 | Boiling Point | 422.8ºC at 760 mmHg | |
| Molecular Formula | C14H14O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 184.1ºC | |
Use of OsthenolOsthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. |
| Name | 7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. |
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| Related Catalog | |
| Target |
hMAO-A:0.26 μM (Ki) hMAO-A:0.74 μM (IC50) |
| References |
[2]. Liao ZC, et al. Zhongguo Zhong Yao Za Zhi. 2017;42(15):2999-3003. |
| Density | 1.203g/cm3 |
|---|---|
| Boiling Point | 422.8ºC at 760 mmHg |
| Molecular Formula | C14H14O3 |
| Molecular Weight | 230.25900 |
| Flash Point | 184.1ºC |
| Exact Mass | 230.09400 |
| PSA | 50.44000 |
| LogP | 3.00730 |
| Vapour Pressure | 9.53E-08mmHg at 25°C |
| Index of Refraction | 1.595 |
| Storage condition | 2-8℃ |
| Precursor 9 | |
|---|---|
| DownStream 3 | |
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| Osthenol |