Coclaurine

Modify Date: 2024-01-08 07:37:35

Coclaurine structure	Common Name	Coclaurine
	CAS Number	486-39-5	Molecular Weight	285.338
	Density	1.2±0.1 g/cm3	Boiling Point	496.9±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₉NO₃	Melting Point	220-221°
	MSDS	N/A	Flash Point	254.3±28.7 °C

Use of Coclaurine

Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].

Name	(RS)-coclaurine
Synonym	More Synonyms

Description	Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR
References	[1]. Sowemimo BO, et al. The isolation of stepharine and coclaurine from Sarcopetalum harveyanum. Lloydia. 1972 Mar;35(1):90-1. [2]. Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.

Description

Coclaurine is a class of tetrahydroisoquinoline alkaloids isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

References

[1]. Sowemimo BO, et al. The isolation of stepharine and coclaurine from Sarcopetalum harveyanum. Lloydia. 1972 Mar;35(1):90-1.

[2]. Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.

Density	1.2±0.1 g/cm3
Boiling Point	496.9±45.0 °C at 760 mmHg
Melting Point	220-221°
Molecular Formula	C₁₇H₁₉NO₃
Molecular Weight	285.338
Flash Point	254.3±28.7 °C
Exact Mass	285.136505
PSA	61.72000
LogP	1.72
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.621