4-Quinolinecarboxylic acid

Modify Date: 2026-07-01 22:35:04

4-Quinolinecarboxylic acid structure	Common Name	4-Quinolinecarboxylic acid
	CAS Number	486-74-8	Molecular Weight	173.168
	Density	1.3±0.1 g/cm3	Boiling Point	348.7±15.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₇NO₂	Melting Point	254-255 °C(lit.)
	MSDS	Chinese USA	Flash Point	164.7±20.4 °C
	Symbol	GHS07	Signal Word	Warning

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	quinoline-4-carboxylic acid
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.3±0.1 g/cm3
Boiling Point	348.7±15.0 °C at 760 mmHg
Melting Point	254-255 °C(lit.)
Molecular Formula	C₁₀H₇NO₂
Molecular Weight	173.168
Flash Point	164.7±20.4 °C
Exact Mass	173.047684
PSA	50.19000
LogP	1.99
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.685
InChIKey	VQMSRUREDGBWKT-UHFFFAOYSA-N
SMILES	O=C(O)c1ccnc2ccccc12

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

4-Quinolinecarboxylic acid MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD3850000

CHEMICAL NAME :: Cinchoninic acid

CAS REGISTRY NUMBER :: 486-74-8

BEILSTEIN REFERENCE NO. :: 0005224

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H7-N-O2

MOLECULAR WEIGHT :: 173.18

WISWESSER LINE NOTATION :: T66 BNJ EVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GD3850000
HS Code	2933499090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:491-35-0 lepidine CAS#:5467-57-2 2-Chloro-4-quin... CAS#:5632-16-6 4-(Bromomethyl)... CAS#:4363-93-3 Quinoline-4-car...
CAS#:5323-57-9 2,4-Quinolinedi... CAS#:124-38-9 Carbon dioxide CAS#:3964-04-3 4-Bromoquinoline CAS#:113-24-6 Sodium 2-oxopro...
CAS#:91-56-5 isatin CAS#:13362-63-5 trans-4-styrylq...
DownStream 10
CAS#:60814-30-4 1-(QUINOLIN-4-Y... CAS#:490-11-9 Cinchomeronic acid CAS#:4363-95-5 4-Quinolinecarb... CAS#:91-22-5 leucoline
CAS#:611-35-8 4-Chloroquinoline CAS#:529-37-3 4(1H)-Quinolinone CAS#:157915-68-9 2-Amino-quinoli... CAS#:10447-29-7 Ethyl 4-quinoli...
CAS#:15733-89-8 2-Hydroxy-4-qui... CAS#:13337-69-4 1,2,3,4-Tetrahy...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey.

Anal. Bioanal. Chem 407 , 6159-70, (2015)

Time-of-flight accurate mass spectrometry (TOF-MS), following a previous chromatographic (gas or liquid chromatography) separation step, is applied to the identification and structural elucidation of ...

Synthesis, characterization and crystal structure of novel mononuclear peroxotungsten(VI) complexes. Insulinomimetic activity of W(VI) and Nb(V) peroxo complexes.

J. Inorg. Biochem. 103(5) , 859-68, (2009)

Two new mononuclear peroxo complexes of tungsten of the formula (gu)(2)[WO(2)(O(2))(2)] (1) and (gu)[WO(O(2))(2)(quin-2-c)] (2a) (where gu(+)=guanidinium ion, CN(3)H(6)(+) and quin-2-c=quinoline-2-car...

Quinoline-4-carboxylic acid.

Acta Crystallogr. C 54 ( Pt 12) , 1883-5, (1998)

The title acid, C10H7NO2, crystallized in the centrosymmetric space group P2(1)/c with one molecule in the asymmetric unit. There is a single hydrogen bond. O-H...N, with a donor-acceptor distance of ...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: qHTS assay for inhibitors of human lactate dehydrogenase
Source: NCGC
Target: N/A
External Id: LDHA

Name: Cytotoxicity against human MCF-10A cells assessed as cell growth inhibition measured ...
Source: ChEMBL
Target: MCF-10A
External Id: CHEMBL5330559

Name: Antiproliferative activity against human MCF7 cells assessed as inhibition of cell gr...
Source: ChEMBL
Target: MCF7
External Id: CHEMBL5330557

Name: Inhibition of HIV1 reverse transcriptase assessed as reduction in [3H]dTTP incorporat...
Source: ChEMBL
Target: Reverse transcriptase/RNaseH
External Id: CHEMBL4373315

Name: Antiproliferative activity against human MCF7ADR cells assessed as inhibition of cell...
Source: ChEMBL
Target: NCI/ADR-RES
External Id: CHEMBL5330558

Name: Antiproliferative activity against human A549 cells assessed as inhibition of cell gr...
Source: ChEMBL
Target: A549
External Id: CHEMBL5330555

Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-FF

Name: Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell...
Source: ChEMBL
Target: HCT-116
External Id: CHEMBL5330556

Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-Ren

Name: Modulation of human Nur77 LBD transiently transfected in HEK293T cells at 100 to 200 ...
Source: ChEMBL
Target: Nuclear receptor subfamily 4immunitygroup A member 1
External Id: CHEMBL5392231

Total 10, Current Page 1 of 1

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00006782

4-Quinolinecarboxylic acid

EINECS 207-640-1

Quinoline-4-carboxylic acid

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of quinoline-4-carboxylic acid?

A: SMILES notation of quinoline-4-carboxylic acid is O=C(O)c1ccnc2ccccc12.

Q: What is the polar surface area (PSA) of quinoline-4-carboxylic acid?

A: Polar surface area (PSA) of quinoline-4-carboxylic acid is 50.19000.

Q: What is the boiling point of quinoline-4-carboxylic acid?

A: Boiling point of quinoline-4-carboxylic acid is 348.7±15.0 °C at 760 mmHg.

Q: What is the molecular weight of quinoline-4-carboxylic acid?

A: Molecular weight of quinoline-4-carboxylic acid is 173.168.

Q: What is the molecular formula of quinoline-4-carboxylic acid?

A: Molecular formula of quinoline-4-carboxylic acid is C10H7NO2.

Q: What are the downstream products of quinoline-4-carboxylic acid?

A: Related downstream products(CAS) of quinoline-4-carboxylic acid: 60814-30-4;490-11-9;4363-95-5;91-22-5;611-35-8;529-37-3;157915-68-9;10447-29-7;15733-89-8;13337-69-4.

Q: What is the InChIKey of quinoline-4-carboxylic acid?

A: InChIKey of quinoline-4-carboxylic acid is VQMSRUREDGBWKT-UHFFFAOYSA-N.

Q: What are the upstream materials of quinoline-4-carboxylic acid?

A: Related upstream materials(CAS) of quinoline-4-carboxylic acid: 491-35-0;5467-57-2;5632-16-6;4363-93-3;5323-57-9;124-38-9;3964-04-3;113-24-6;91-56-5;13362-63-5.

Q: What is the melting point of quinoline-4-carboxylic acid?

A: Melting point of quinoline-4-carboxylic acid is 254-255 °C(lit.).

Q: What English synonyms does quinoline-4-carboxylic acid have?

A: English synonyms of quinoline-4-carboxylic acid: MFCD00006782, 4-Quinolinecarboxylic acid, EINECS 207-640-1, Quinoline-4-carboxylic acid.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Quinolinecarboxylic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Quinoline-4-carboxylic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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4-Quinolinecarboxylic acid

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