CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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RT0620000
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CHEMICAL NAME :
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Pachycarpine
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CAS REGISTRY NUMBER :
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492-08-0
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BEILSTEIN REFERENCE NO. :
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3540601
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C15-H26-N2
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MOLECULAR WEIGHT :
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234.43
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WISWESSER LINE NOTATION :
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T C66 K66 A HN PNTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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89100 ug/kg
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TOXIC EFFECTS :
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Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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SHIYDO Shaanxi Xinyiyao. Shaanxi New Medical. (Shaanxi Renmin Chubanshe, Xi'an, Shaanxi, Peop. Rep. China) V.1- 1972- Volume(issue)/page/year: 11(6),53,1982
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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90 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 21(5),46,1958
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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26 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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32ZCAI "Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich, D.A., Moscow, First Moscow Medical Institute, 1967 Volume(issue)/page/year: -,175,1967
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