MLS 0038949
MLS 0038949 structure
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Common Name | MLS 0038949 | ||
|---|---|---|---|---|
| CAS Number | 496014-13-2 | Molecular Weight | 344.38500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H16N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MLS 0038949MLS 0038949 is a potent, selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor with IC50 of 0.19 uM, shows no activity against IAP and PLAP (IC50>100 uM). |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C17H16N2O4S |
|---|---|
| Molecular Weight | 344.38500 |
| Exact Mass | 344.08300 |
| PSA | 85.90000 |
| LogP | 4.20660 |
| InChIKey | JZSPHTPWUXNQGB-UHFFFAOYSA-N |
| SMILES | COc1ccc(OC)c(S(=O)(=O)Nc2cnc3ccccc3c2)c1 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
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| DownStream 0 | |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2,5-Dimethoxy-hexamethylen-bis-mercuriacetat |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: Main uses of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide: MLS 0038949 is a potent, selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor with IC50 of 0.19 uM, shows no activity against IAP and PLAP (IC50>100 uM). |
| Q: What is the molecular weight of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: Molecular weight of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is 344.38500. |
| Q: What is the SMILES notation of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: SMILES notation of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is COc1ccc(OC)c(S(=O)(=O)Nc2cnc3ccccc3c2)c1. |
| Q: What English synonyms does 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide have? |
| A: English synonyms of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide: 2,5-Dimethoxy-hexamethylen-bis-mercuriacetat. |
| Q: What is the molecular formula of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: Molecular formula of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is C17H16N2O4S. |
| Q: What is the LogP of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: LogP of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is 4.20660. |
| Q: What is the polar surface area (PSA) of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: Polar surface area (PSA) of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is 85.90000. |
| Q: What is the CAS number of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: CAS number of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is 496014-13-2. |
| Q: What is the English name of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: The English name of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide is 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide. |
| Q: What are the upstream materials of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide? |
| A: Related upstream materials(CAS) of 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide: 580-17-6;1483-28-9. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |