3-Quinolinamine

Modify Date: 2024-01-06 12:39:56

3-Quinolinamine Structure
3-Quinolinamine structure
Common Name 3-Quinolinamine
CAS Number 580-17-6 Molecular Weight 144.173
Density 1.2±0.1 g/cm3 Boiling Point 311.4±15.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point 91-92 °C(lit.)
MSDS Chinese USA Flash Point 167.8±7.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3-Aminoquinoline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 311.4±15.0 °C at 760 mmHg
Melting Point 91-92 °C(lit.)
Molecular Formula C9H8N2
Molecular Weight 144.173
Flash Point 167.8±7.6 °C
Exact Mass 144.068741
PSA 38.91000
LogP 1.49
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.708
Water Solubility slightly soluble in hot water

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA9622000
CHEMICAL NAME :
Quinoline, 3-amino-
CAS REGISTRY NUMBER :
580-17-6
BEILSTEIN REFERENCE NO. :
0113317
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H8-N2
MOLECULAR WEIGHT :
144.19
WISWESSER LINE NOTATION :
T66 BNJ DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
5 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 187,191,1987

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R20/21/22;R36/37/38;R68
Safety Phrases S26-S36-S36/37/39-S22
RIDADR 2811.0
WGK Germany 3
RTECS VA9622000
HS Code 29334990

 Synthetic Route

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles10

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We previously reported that knockout mice for α1,6-fucosyltransferase (Fut8), which catalyzes the biosynthesis of core-fucose in N-glycans, develop emphysema and that Fut8 heterozygous knockout mice a...

Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS.

Analyst 140(2) , 467-75, (2014)

Tandem mass spectrometry (MS/MS)-based relative quantification by isobaric labeling is a useful technique to compare different metabolic expression levels in biological systems. For the first time, we...

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging.

Anal. Bioanal. Chem 406(19) , 4601-10, (2014)

The combination of ultrahigh-resolution mass spectrometry imaging (UHRMSI) and ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS) was used for the identifi...

 Synonyms

EINECS 209-455-1
MFCD00006772
3-Aminoquinoline
3-Quinolinamine
quinolin-3-amine
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