2-methylthio-4-chloropyrimidine

Modify Date: 2024-01-02 12:10:31

2-methylthio-4-chloropyrimidine Structure
2-methylthio-4-chloropyrimidine structure
Common Name 2-methylthio-4-chloropyrimidine
CAS Number 49844-90-8 Molecular Weight 160.625
Density 1.4±0.1 g/cm3 Boiling Point 243.1±13.0 °C at 760 mmHg
Molecular Formula C5H5ClN2S Melting Point −2 °C(lit.)
MSDS USA Flash Point 100.8±19.8 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-Chloro-2-methylthiopyrimidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 243.1±13.0 °C at 760 mmHg
Melting Point −2 °C(lit.)
Molecular Formula C5H5ClN2S
Molecular Weight 160.625
Flash Point 100.8±19.8 °C
Exact Mass 159.986191
PSA 51.08000
LogP 1.81
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.595

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 1760 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

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The total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involve...

Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.

J. Med. Chem. 50 , 1146, (2007)

By the screening of a combinatorial library for inhibitors of nitric oxide (NO) formation by the inducible isoform of nitric oxide synthase (iNOS) using a whole-cell assay, 2-(imidazol-1-yl)pyrimidine...

Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides.

J. Med. Chem. 50 , 3497, (2007)

The vanilloid receptor-1 (VR1 or TRPV1) is a member of the transient receptor potential (TRP) family of ion channels and plays a role as an integrator of multiple pain-producing stimuli. From a high-t...

 Synonyms

2-methylthio-4-chloropyrimidine
4-Chloro-2-(methylthio)pyrimidine
4-Chloro-2-methylthiopyrimidine
MFCD00006083
4-Chloro-2-(methylsulfanyl)pyrimidine
Pyrimidine, 4-chloro-2-(methylthio)-
4-chloro-2-methylsulfanylpyrimidine
EINECS 256-500-6
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