Pritumumab

Modify Date: 2024-01-03 16:56:07

Pritumumab Structure
Pritumumab structure
Common Name Pritumumab
CAS Number 499212-74-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pritumumab


Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research[1][2].

 Names

Name Pritumumab

 Pritumumab Biological Activity

Description Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research[1][2].
Related Catalog
In Vivo Pritumumab 在裸鼠中有效阻止肿瘤生长,但在SCID小鼠中无效[1]。 Pritumumab 只有在完整的细胞介导免疫存在的情况下,才能限制体内异种移植胶质瘤肿瘤的生长[1]。
References

[1]. Santosh Kesari, et al. Pritumumab binding to glioma cells induces ADCC and inhibits tumor growth. ASCO Annual Meeting I. 2017.

[2]. Hugwil AV. The meaning of the anti-cancer antibody CLN-IgG (Pritumumab) generated by human × human hybridoma technology against the cyto-skeletal protein, vimentin, in the course of the treatment of malignancy. Med Hypotheses. 2013 Sep;81(3):489-95.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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