HYPOGLYCINB

Modify Date: 2024-01-12 16:21:07

HYPOGLYCINB Structure
HYPOGLYCINB structure
Common Name HYPOGLYCINB
CAS Number 502-37-4 Molecular Weight 270.28200
Density 1.33g/cm3 Boiling Point 592.8ºC at 760mmHg
Molecular Formula C12H18N2O5 Melting Point N/A
MSDS N/A Flash Point 312.3ºC

 Names

Name L-γ-Glutamyl-3-[(1R)-2-methylenecyclopropyl]alanine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.33g/cm3
Boiling Point 592.8ºC at 760mmHg
Molecular Formula C12H18N2O5
Molecular Weight 270.28200
Flash Point 312.3ºC
Exact Mass 270.12200
PSA 133.21000
LogP 1.25470
Index of Refraction 1.562

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY6330000
CHEMICAL NAME :
Alanine, N-L-gamma-glutamyl-3-(methylenecyclopropyl)-
CAS REGISTRY NUMBER :
502-37-4
BEILSTEIN REFERENCE NO. :
3162184
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H18-N2-O5
MOLECULAR WEIGHT :
270.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Endocrine - hypoglycemia
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intrauterine
DOSE :
500 ug/kg
SEX/DURATION :
female 14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 4,246,1971

 Synthetic Route

~%

HYPOGLYCINB Structure

HYPOGLYCINB

CAS#:502-37-4

Literature: Joehl; Stoll Helvetica Chimica Acta, 1959 , vol. 42, p. 716,717

~%

HYPOGLYCINB Structure

HYPOGLYCINB

CAS#:502-37-4

Literature: Joehl; Stoll Helvetica Chimica Acta, 1959 , vol. 42, p. 716,717

~%

HYPOGLYCINB Structure

HYPOGLYCINB

CAS#:502-37-4

Literature: Joehl; Stoll Helvetica Chimica Acta, 1959 , vol. 42, p. 716,717

~%

HYPOGLYCINB Structure

HYPOGLYCINB

CAS#:502-37-4

Literature: Hassall; John Tetrahedron Letters, 1959 , # 3 p. 7

 Synonyms

Hypoglyin-B
(S)-2-L-alanylamino-butyric acid
(S)-2-L-Alanylamino-buttersaeure
L-2-(L-2-Amino-propionylamino)-buttersaeure
N-L-Alanyl-L-2-amino-buttersaeure