Fluoroacetonitrile

Modify Date: 2025-08-20 19:53:24

Fluoroacetonitrile Structure
Fluoroacetonitrile structure
Common Name Fluoroacetonitrile
CAS Number 503-20-8 Molecular Weight 59.042
Density 1.0±0.1 g/cm3 Boiling Point 79.5±0.0 °C at 760 mmHg
Molecular Formula C2H2FN Melting Point -13 °C
MSDS Chinese USA Flash Point -13.9±0.0 °C
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

 Names

Name Fluoroacetonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 79.5±0.0 °C at 760 mmHg
Melting Point -13 °C
Molecular Formula C2H2FN
Molecular Weight 59.042
Flash Point -13.9±0.0 °C
Exact Mass 59.017128
PSA 23.79000
LogP -0.39
Vapour Pressure 88.8±0.1 mmHg at 25°C
Index of Refraction 1.303

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM0175000
CHEMICAL NAME :
Acetonitrile, fluoro-
CAS REGISTRY NUMBER :
503-20-8
BEILSTEIN REFERENCE NO. :
1697891
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C2-H2-F-N
MOLECULAR WEIGHT :
59.05
WISWESSER LINE NOTATION :
NC1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 78,3484,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H225-H301 + H311 + H331-H315-H319-H335
Precautionary Statements P210-P261-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F:Flammable;T:Toxic;
Risk Phrases R11;R23/24/25;R36/37/38
Safety Phrases S16-S26-S27-S36/37/39-S45
RIDADR UN 3273
RTECS AM0175000
Packaging Group II
Hazard Class 3.1
HS Code 2926909090

 Synthetic Route

~%

Fluoroacetonitrile Structure

Fluoroacetonitrile

CAS#:503-20-8

Literature: Swarts Bulletin des Societes Chimiques Belges, 1922 , vol. 31, p. 364 Chem. Zentralbl., 1923 , vol. 94, # III p. 117

~%

Fluoroacetonitrile Structure

Fluoroacetonitrile

CAS#:503-20-8

Literature: Kitano et al. Kogyo Kagaku Zasshi, 1955 , vol. 58, p. 224 Chem.Abstr., 1956 , p. 4108

~%

Fluoroacetonitrile Structure

Fluoroacetonitrile

CAS#:503-20-8

Literature: Tyndall, Geoffrey S.; Orlando, John J.; Wallington, Timothy J.; Sehested, Jens; Nielsen, Ole J. Journal of Physical Chemistry, 1996 , vol. 100, # 2 p. 660 - 668

~%

Fluoroacetonitrile Structure

Fluoroacetonitrile

CAS#:503-20-8

Literature: Bergmann; Shahak Chemistry and Industry (London, United Kingdom), 1958 , p. 157

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles2

More Articles
2-Fluoromethyl-4, 4, 6-trimetiiyl-1, 3-oxasine as a new reagent for the preparation of a-fluoroaldehydes. Patrick TB, et al.

Tetrahedron Lett. 31(2) , 179-82, (1990)

Preparative flow techniques. 2. Grignard addition reaction on fluoroaceto-nitrile: Synthesis of 2-amino-2-fluoromethyl-3-pentenenitrile. Gerhart F, et al.

J. Fluor. Chem. 50(2) , 243-49, (1990)

 Synonyms

Acetonitrile, 2-fluoro-
MFCD00009969
Fluoroacetonitrile
2-fluoroacetonitrile
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