2-Thiohydantoin
2-Thiohydantoin structure
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Common Name | 2-Thiohydantoin | ||
|---|---|---|---|---|
| CAS Number | 503-87-7 | Molecular Weight | 116.142 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C3H4N2OS | Melting Point | 229-231 °C (dec.)(lit.) | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2-Thiohydantoin2-Thiohydantoin acts as an inhibitor for the corrosion of mild steel in 0.1 M HCl and its inhibition efficiency is both concentration and immersion time dependent[1]. |
Summary: 2-Thiohydantoin (2-Thioxo-4-imidazolidinone NSC 11772), with molecular formula C3H4N2OS and molecular weight 116.142, is a potent inhibitor of mutant IDH1, reducing cellular D2HG concentration, histone methylation levels, and proliferation of IDH1 R132H-mutated BT142 glioma stem-like cells. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-Thioxo-4-imidazolidinone NSC 11772 |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 2-Thiohydantoin acts as an inhibitor for the corrosion of mild steel in 0.1 M HCl and its inhibition efficiency is both concentration and immersion time dependent[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Melting Point | 229-231 °C (dec.)(lit.) |
| Molecular Formula | C3H4N2OS |
| Molecular Weight | 116.142 |
| Exact Mass | 116.004433 |
| PSA | 73.22000 |
| LogP | -0.62 |
| Vapour density | 4 (vs air) |
| Index of Refraction | 1.655 |
| InChIKey | UGWULZWUXSCWPX-UHFFFAOYSA-N |
| SMILES | O=C1CNC(=S)N1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xn:Harmful; |
|---|---|
| Risk Phrases | R22 |
| Safety Phrases | S36 |
| WGK Germany | 3 |
| RTECS | MU4200000 |
| HS Code | 2933990090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00005277 |
| 2-thioxoimidazolidin-4-one |
| thiohydantoin |
| 2-sulfanylideneimidazolidin-4-one |
| 2-Thioxo-4-imidazolidinone |
| EINECS 207-977-4 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: CAS number of 2-Thioxo-4-imidazolidinone NSC 11772 is 503-87-7. |
| Q: What are the uses of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: Main uses of 2-Thioxo-4-imidazolidinone NSC 11772: 2-Thiohydantoin acts as an inhibitor for the corrosion of mild steel in 0.1 M HCl and its inhibition efficiency is both concentration and immersion time dependent[1]. |
| Q: What English synonyms does 2-Thioxo-4-imidazolidinone NSC 11772 have? |
| A: English synonyms of 2-Thioxo-4-imidazolidinone NSC 11772: MFCD00005277, 2-thioxoimidazolidin-4-one, thiohydantoin, 2-sulfanylideneimidazolidin-4-one, 2-Thioxo-4-imidazolidinone, EINECS 207-977-4. |
| Q: What is the molecular weight of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: Molecular weight of 2-Thioxo-4-imidazolidinone NSC 11772 is 116.142. |
| Q: What is the LogP of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: LogP of 2-Thioxo-4-imidazolidinone NSC 11772 is -0.62. |
| Q: What is the safety information for 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: Safety information for 2-Thioxo-4-imidazolidinone NSC 11772: S36. |
| Q: What is the molecular formula of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: Molecular formula of 2-Thioxo-4-imidazolidinone NSC 11772 is C3H4N2OS. |
| Q: What is the SMILES notation of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: SMILES notation of 2-Thioxo-4-imidazolidinone NSC 11772 is O=C1CNC(=S)N1. |
| Q: What is the polar surface area (PSA) of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: Polar surface area (PSA) of 2-Thioxo-4-imidazolidinone NSC 11772 is 73.22000. |
| Q: What is the English name of 2-Thioxo-4-imidazolidinone NSC 11772? |
| A: The English name of 2-Thioxo-4-imidazolidinone NSC 11772 is 2-Thioxo-4-imidazolidinone NSC 11772. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |