NU-7163 structure
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Common Name | NU-7163 | ||
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CAS Number | 503468-03-9 | Molecular Weight | 295.332 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 461.3±45.0 °C at 760 mmHg | |
Molecular Formula | C18H17NO3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 232.8±28.7 °C |
Use of NU-7163A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM; exhibits selectivity for DNA-PK versus related enzymes ATM, ATR, mTOR, and p110α; sensitizes the HeLa cells to the cytotoxic effects of ionizing radiation in vitro. |
Name | 2-(2-methylmorpholin-4-yl)benzo(h)chromen-4-one |
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Synonym | More Synonyms |
Description | A poten and selective, ATP-competitive DNA-PK inhibitor with IC50 of 0.19 uM, Ki of 24 nM; exhibits selectivity for DNA-PK versus related enzymes ATM, ATR, mTOR, and p110α; sensitizes the HeLa cells to the cytotoxic effects of ionizing radiation in vitro. |
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References | References 1. Griffin RJ, et al. J Med Chem. 2005 Jan 27;48(2):569-85. View Related Products by Target DNA-PK |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 461.3±45.0 °C at 760 mmHg |
Molecular Formula | C18H17NO3 |
Molecular Weight | 295.332 |
Flash Point | 232.8±28.7 °C |
Exact Mass | 295.120850 |
LogP | 3.78 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.646 |
2-(2-methylmorpholin-4-yl)-4H-benzo[h]chromen-4-one |
4H-Naphtho[1,2-b]pyran-4-one, 2-(2-methyl-4-morpholinyl)- |
2-(2-Methyl-4-morpholinyl)-4H-benzo[h]chromen-4-one |
2-(2-methylmorpholin-4-yl)benzo(h)chromen-4-one |