1,4-Dithiane

Modify Date: 2024-01-04 16:50:01

1,4-Dithiane Structure
1,4-Dithiane structure
Common Name 1,4-Dithiane
CAS Number 505-29-3 Molecular Weight 120.236
Density 1.1±0.1 g/cm3 Boiling Point 200.5±15.0 °C at 760 mmHg
Molecular Formula C4H8S2 Melting Point 110-112ºC
MSDS Chinese USA Flash Point 82.1±17.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1,4-dithiane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 200.5±15.0 °C at 760 mmHg
Melting Point 110-112ºC
Molecular Formula C4H8S2
Molecular Weight 120.236
Flash Point 82.1±17.4 °C
Exact Mass 120.006737
PSA 50.60000
LogP 1.12
Vapour Pressure 0.5±0.4 mmHg at 25°C
Index of Refraction 1.574
Storage condition 2-8°C
Stability Stable. Incompatible with strong oxidizing agents. Probably combustible.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JO5069000
CHEMICAL NAME :
p-Dithiane
CAS REGISTRY NUMBER :
505-29-3
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C4-H8-S2
MOLECULAR WEIGHT :
120.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2768 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18900 mg/kg/90D-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
4 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 321,213,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4362 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR UN 3335
WGK Germany 2
RTECS JO5069000
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

More Articles
Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test.

Mutat. Res. 321(4) , 213-8, (1994)

1,3-Dithiane and 1,4-dithiane are the sulfur-containing Maillard reaction products (MRPs) which have been found in boiled beef extracts. In this study the genotoxicity of these products was examined u...

Analysis, characterization, and purification: requirements for toxicological evaluation of 1,4-dithiane.

J. Chromatogr. A. 467(1) , 159-66, (1989)

1,4-Dithiane is an organo-sulfur chemical associated with production and storage of munitions. Toxicological evaluation of this chemical was scheduled in rats because of the paucity of such informatio...

 Synonyms

1,4-Dithiane
Tetrahydro-1,4-dithiin,
p-Dithiane
dihydro-1,4-dithiin
EINECS 208-007-2
1,4-Dithiacyclohexane
Diethylene disulfide
1,4-dithian
MFCD00006658
1,4-Dithiin,tetrahydro
p-Dithiin,tetrahydro
p-Dithane
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