trimethyloxirane

DATA ITEMS CITED :

7

MOLECULAR FORMULA :

C5-H10-O

MOLECULAR WEIGHT :

86.15

WISWESSER LINE NOTATION :

T3OTJ B1 B1 C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2635 mg/kg

TOXIC EFFECTS :

Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - excitement

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>7340 ppm/4H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1410 mg/kg

TOXIC EFFECTS :

Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - excitement

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2600 mg/kg

TOXIC EFFECTS :

Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - excitement

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1513 mg/kg

TOXIC EFFECTS :

Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - excitement

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - rat Lymphocyte

DOSE/DURATION :

3 gm/L

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 347,9,1995