Totarol

Modify Date: 2025-08-21 10:06:26

Totarol Structure
Totarol structure
Common Name Totarol
CAS Number 511-15-9 Molecular Weight 284.479
Density 0.9±0.1 g/cm3 Boiling Point 346.1±37.0 °C at 760 mmHg
Molecular Formula C20H30O Melting Point 128-132ºC(lit.)
MSDS N/A Flash Point 163.0±15.1 °C

 Use of Totarol


(+)-Totarol is a diterpenoid compound isolated from Podocarpus spp.. (+)-Totarol is a potent antioxidant and antibacterial agent[1].

 Names

Name Totarol
Synonym More Synonyms

 Totarol Biological Activity

Description (+)-Totarol is a diterpenoid compound isolated from Podocarpus spp.. (+)-Totarol is a potent antioxidant and antibacterial agent[1].
Related Catalog
References

[1]. Bernabeu A, et al. A MAS-NMR study of the location of (+)-totarol, a diterpenoid bioactive molecule, in phospholipid model membranes. Chem Phys Lipids. 2002;119(1-2):33-39.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 346.1±37.0 °C at 760 mmHg
Melting Point 128-132ºC(lit.)
Molecular Formula C20H30O
Molecular Weight 284.479
Flash Point 163.0±15.1 °C
Exact Mass 284.250397
PSA 20.23000
LogP 8.76
Vapour Pressure 0.0±0.4 mmHg at 25°C
Index of Refraction 1.513
InChIKey ZRVDANDJSTYELM-FXAWDEMLSA-N
SMILES CC(C)c1c(O)ccc2c1CCC1C(C)(C)CCCC21C

 Safety Information

Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
WGK Germany 3

 TotarolBioassay

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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: Antimicrobial activity against Staphylococcus aureus 1199B expressing NorA pump
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL955404
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction i...
Source: ChEMBL
Target: Quinolone resistance protein NorA
External Id: CHEMBL955401
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Ratio of inhibition of CHO cells to IC50 for chloroquine-resistant Plasmodium falcipa...
Source: ChEMBL
Target: N/A
External Id: CHEMBL955403
Name: Inhibition of NorA efflux pump in Staphylococcus aureus K3092 assessed as reduction i...
Source: ChEMBL
Target: Quinolone resistance protein NorA
External Id: CHEMBL955402
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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 Synonyms

14-Isopropylpodocarpa-8,11,13-trien-13-ol
4b-S-trans-8,8-trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol
14-Isopropyl-13-methylpodocarpa-8,11,13-triene
2-PHENANTHRENOL,4B,5,6,7,8,8A
trans-Totarol
4BS TRANS,8,8-TRIMETHYL4B,5,6,7,8,8A,9,1
Podocarpa-8,11,13-trien-13-ol,14-isopropyl
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