4-(2-amino-2-methyl-propyl)aniline

Modify Date: 2024-01-15 11:17:25

4-(2-amino-2-methyl-propyl)aniline Structure
4-(2-amino-2-methyl-propyl)aniline structure
Common Name 4-(2-amino-2-methyl-propyl)aniline
CAS Number 51131-55-6 Molecular Weight 164.24700
Density 1.018g/cm3 Boiling Point 288.8ºC at 760 mmHg
Molecular Formula C10H16N2 Melting Point N/A
MSDS N/A Flash Point 151.7ºC

 Names

Name 4-(2-amino-2-methylpropyl)aniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.018g/cm3
Boiling Point 288.8ºC at 760 mmHg
Molecular Formula C10H16N2
Molecular Weight 164.24700
Flash Point 151.7ºC
Exact Mass 164.13100
PSA 52.04000
LogP 2.83010
Index of Refraction 1.568

 Synthetic Route

~0%

4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2009/52078 A1, 2009 ; Location in patent: Page/Page column 79 ; WO 2009/052078 A1

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4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: Theravance, Inc. Patent: US2005/159448 A1, 2005 ; Location in patent: Page/Page column 19 ; US 20050159448 A1

~77%

4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: Cowan, J. A. Tetrahedron Letters, 1986 , vol. 27, # 10 p. 1205 - 1208

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4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: Milecki, Jan; Baker, Stephen P.; Standifer, Kelly M.; Ishizu, Takashi; Chida, Yasuhiro; et al. Journal of Medicinal Chemistry, 1987 , vol. 30, # 9 p. 1563 - 1566

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Detail
Literature: Allied Chemical Corporation Patent: US4024185 A1, 1977 ;

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4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: Milecki, Jan; Baker, Stephen P.; Standifer, Kelly M.; Ishizu, Takashi; Chida, Yasuhiro; et al. Journal of Medicinal Chemistry, 1987 , vol. 30, # 9 p. 1563 - 1566

~%

4-(2-amino-2-methyl-propyl)aniline Structure

4-(2-amino-2-me...

CAS#:51131-55-6

Literature: Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

 Synonyms

2-Amino-2-methyl-1-(4-amino-phenyl)-propan
2-Amino-2-methyl-1-(4-aminophenyl)propane
4-(2-amino-2-methylpropyl)phenylamine
2-(4-aminophenyl)-1,1-dimethylethylamine