Substance P (6-11)
Modify Date: 2025-08-27 10:06:20
Substance P (6-11) structure
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Common Name | Substance P (6-11) | ||
|---|---|---|---|---|
| CAS Number | 51165-07-2 | Molecular Weight | 740.91200 | |
| Density | 1.24g/cm3 | Boiling Point | 1198.9ºC at 760 mmHg | |
| Molecular Formula | C36H52N8O7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 678.9ºC | |
Use of Substance P (6-11)Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (Substance P (HY-P0201)). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect[1][2]. |
| Name | Substance P (6-11) |
|---|---|
| Synonym | More Synonyms |
| Description | Substance P (6-11) is the C-terminal hexapeptideamide of Substance P (Substance P (HY-P0201)). Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Substance P(6-11) 在大鼠膀胱中刺激 [3H]-肌醇一磷酸 ([3H]-IP1) 的形成，EC50 值为 4 nM。 |
| In Vivo | Substance P (6-11) (0.1-10 nM) 以剂量依赖的方式抑制大鼠胰腺分泌胰岛素和胰高血糖素。相反，在犬胰腺中，Substance P (6-11) (1-10 nM) 会增强胰岛素、胰高血糖素和生长抑素的释放[2]。 |
| References |
| Density | 1.24g/cm3 |
|---|---|
| Boiling Point | 1198.9ºC at 760 mmHg |
| Molecular Formula | C36H52N8O7S |
| Molecular Weight | 740.91200 |
| Flash Point | 678.9ºC |
| Exact Mass | 740.36800 |
| PSA | 283.00000 |
| LogP | 3.45990 |
| Index of Refraction | 1.579 |
| substance P(6-11) |
| [Gln6]substance P(6-11) |
| glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methionine amide |
| SUBSTANCE P FRAGMENT 6-11) |
| L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 |
| HEXA-SUBSTANCE P |
| SUBSTANCE-P-(-6-11) HEXA-SUBSTANCE P |
| H-GLN-PHE-PHE-GLY-LEU-MET-NH2 |
| GLN-PHE-PHE-GLY-LEU-MET-NH2 |