2',3'-Dideoxy-3'-fluorocytidine

Modify Date: 2024-01-05 11:21:11

2',3'-Dideoxy-3'-fluorocytidine Structure
2',3'-Dideoxy-3'-fluorocytidine structure
 Common Name 2',3'-Dideoxy-3'-fluorocytidine
CAS Number 51246-79-8 Molecular Weight 229.21
Density 1.7±0.1 g/cm3 Boiling Point 418.0±55.0 °C at 760 mmHg
Molecular Formula C9H12FN3O3 Melting Point N/A
MSDS N/A Flash Point 206.6±31.5 °C

 Use of 2',3'-Dideoxy-3'-fluorocytidine


2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(3-fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)cytosine
Synonym More Synonyms

 2',3'-Dideoxy-3'-fluorocytidine Biological Activity

Description 2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 418.0±55.0 °C at 760 mmHg
Molecular Formula C9H12FN3O3
Molecular Weight 229.21
Flash Point 206.6±31.5 °C
Exact Mass 229.086273
PSA 90.37000
LogP -1.07
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.665

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

Cytidine, 2',3'-dideoxy-3'-fluoro-
2',3'-Dideoxy-3'-fluorocytidine
2'-deoxy-3'-fluoro-d-cytidine
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