2',3'-Dideoxy-3'-fluoroadenosine

Modify Date: 2024-02-01 11:31:45

2',3'-Dideoxy-3'-fluoroadenosine Structure
2',3'-Dideoxy-3'-fluoroadenosine structure
Common Name 2',3'-Dideoxy-3'-fluoroadenosine
CAS Number 87418-35-7 Molecular Weight 253.23
Density 1.9±0.1 g/cm3 Boiling Point 541.3±60.0 °C at 760 mmHg
Molecular Formula C10H12FN5O2 Melting Point N/A
MSDS N/A Flash Point 281.2±32.9 °C

 Use of 2',3'-Dideoxy-3'-fluoroadenosine


2′,3′-Dideoxy-3′-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-(2',3'-dideoxy-3'-fluoro-β-D-ribofuranosyl)adenine
Synonym More Synonyms

 2',3'-Dideoxy-3'-fluoroadenosine Biological Activity

Description 2′,3′-Dideoxy-3′-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 541.3±60.0 °C at 760 mmHg
Molecular Formula C10H12FN5O2
Molecular Weight 253.23
Flash Point 281.2±32.9 °C
Exact Mass 253.097504
PSA 99.08000
LogP -0.20
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.796

 Safety Information

HS Code 2934999090

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

9-(3-Fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)adenine
3'-Fluoro-2',3'-dideoxyadenosine
3'-
2',3'-Dideoxy-3'-fluoroadenosine
Adenosine, 2',3'-dideoxy-3'-fluoro-
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