Rubropunctamine

Modify Date: 2024-01-08 02:55:19

Rubropunctamine structure	Common Name	Rubropunctamine
	CAS Number	514-66-9	Molecular Weight	353.41200
	Density	1.22g/cm3	Boiling Point	647.1ºC at 760 mmHg
	Molecular Formula	C₂₁H₂₃NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	345.1ºC

Use of Rubropunctamine

Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities[1][2].

Name	(9aR)-3-hexanoyl-9a-methyl-6-[(E)-prop-1-enyl]-7H-furo[3,2-g]isoquinoline-2,9-dione
Synonym	More Synonyms

Description	Rubropunctamine is a red azaphilone pigment isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctamine has anti-inflammation activities[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Rubropunctamine (0.32-32 nM; 48 h) inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with an IC50 of 433 mol ratio/32 pmol TPA[1]. Rubropunctamine (1 h) exhibits moderate scavenging activity (inhibitory ratio (IR)=1.5) against NO generation by (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1) in normal human hepato cells[1].
In Vivo	Rubropunctamine inhibits TPA-induced inflammation in mice, with an ID50 of 0.32 mg/ear[1].
References	[1]. Akihisa T, et, al. Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (red-mold rice) and their chemopreventive effects. J Agric Food Chem. 2005 Feb 9;53(3):562-5. [2]. Patakova P. Monascus secondary metabolites: production and biological activity. J Ind Microbiol Biotechnol. 2013 Feb;40(2):169-81.

Density	1.22g/cm3
Boiling Point	647.1ºC at 760 mmHg
Molecular Formula	C₂₁H₂₃NO₄
Molecular Weight	353.41200
Flash Point	345.1ºC
Exact Mass	353.16300
PSA	76.23000
LogP	3.06720
Index of Refraction	1.59

Rubropunctamine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Rubropunctatin
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Rubropunctamine
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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