Dehydroergosterol

Modify Date: 2024-07-28 21:20:44

Dehydroergosterol Structure
Dehydroergosterol structure
Common Name Dehydroergosterol
CAS Number 516-85-8 Molecular Weight 394.63200
Density 1.02g/cm3 Boiling Point 520.6ºC at 760 mmHg
Molecular Formula C28H42O Melting Point 146°C (lit.)
MSDS Chinese USA Flash Point 221ºC
Symbol GHS08
GHS08
Signal Word Warning

 Use of Dehydroergosterol


Dehydroergosterol is a naturally occurring fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes. [1] It is readily bound by cholesterol-binding proteins and has been used to probe the sterol environment in real time and elucidate intracellular sterol transport in organisms. [1] References: [1]. McIntosh, AL, Atshaves, BP, Huang, H., et al. A Fluorescent Technique to Study Cholesterol Transport Using Dehydroergosterol. Lipids 43(12), 1185-1208 (2008).

 Names

Name dehydroergosterol
Synonym More Synonyms

 Dehydroergosterol Biological Activity

Description Dehydroergosterol is a naturally occurring fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes. [1] It is readily bound by cholesterol-binding proteins and has been used to probe the sterol environment in real time and elucidate intracellular sterol transport in organisms. [1] References: [1]. McIntosh, AL, Atshaves, BP, Huang, H., et al. A Fluorescent Technique to Study Cholesterol Transport Using Dehydroergosterol. Lipids 43(12), 1185-1208 (2008).
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 Chemical & Physical Properties

Density 1.02g/cm3
Boiling Point 520.6ºC at 760 mmHg
Melting Point 146°C (lit.)
Molecular Formula C28H42O
Molecular Weight 394.63200
Flash Point 221ºC
Exact Mass 394.32400
PSA 20.23000
LogP 7.25090
Index of Refraction 1.553
Storage condition 20°C

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351-H373
Hazard Codes Xn
Risk Phrases 40
Safety Phrases 36/37
RIDADR NONH for all modes of transport

 Articles27

More Articles
Lipid droplet changes in proliferating and quiescent 3T3 fibroblasts.

Histochem. Cell Biol. 129(5) , 611-21, (2008)

Lipid droplets (LDs) are fat-storing organelles present in virtually all eukaryotic cells and involved in many aspects of cell biology related to lipid metabolism and cholesterol homeostasis. In this ...

Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells.

Histochem. Cell Biol. 130(5) , 891-908, (2008)

Distribution and dynamics of cholesterol in the plasma membrane as well as internalization pathways for sterol from the cell surface are of great cell biological interest. Here, UV-sensitive wide fiel...

Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol.

Chem. Phys. Lipids 164(3) , 221-35, (2011)

Cholesterol with BODIPY at carbon-24 of the side chain (BCh2) has recently been introduced as new cholesterol probe with superior fluorescence properties. We compare BCh2 with the intrinsically fluore...

 Synonyms

Dehydroergosterol
ergosta-5,7,9(11),22-tetraen-3ß-ol
(3S,10S,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,12,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol
Ergosta-5,7,9(11),22-tetraen-3β-ol