Dehydroergosterol structure
|
Common Name | Dehydroergosterol | ||
---|---|---|---|---|
CAS Number | 516-85-8 | Molecular Weight | 394.63200 | |
Density | 1.02g/cm3 | Boiling Point | 520.6ºC at 760 mmHg | |
Molecular Formula | C28H42O | Melting Point | 146°C (lit.) | |
MSDS | Chinese USA | Flash Point | 221ºC | |
Symbol |
GHS08 |
Signal Word | Warning |
Use of DehydroergosterolDehydroergosterol is a naturally occurring fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes. [1] It is readily bound by cholesterol-binding proteins and has been used to probe the sterol environment in real time and elucidate intracellular sterol transport in organisms. [1] References: [1]. McIntosh, AL, Atshaves, BP, Huang, H., et al. A Fluorescent Technique to Study Cholesterol Transport Using Dehydroergosterol. Lipids 43(12), 1185-1208 (2008). |
Name | dehydroergosterol |
---|---|
Synonym | More Synonyms |
Description | Dehydroergosterol is a naturally occurring fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes. [1] It is readily bound by cholesterol-binding proteins and has been used to probe the sterol environment in real time and elucidate intracellular sterol transport in organisms. [1] References: [1]. McIntosh, AL, Atshaves, BP, Huang, H., et al. A Fluorescent Technique to Study Cholesterol Transport Using Dehydroergosterol. Lipids 43(12), 1185-1208 (2008). |
---|---|
Related Catalog |
Density | 1.02g/cm3 |
---|---|
Boiling Point | 520.6ºC at 760 mmHg |
Melting Point | 146°C (lit.) |
Molecular Formula | C28H42O |
Molecular Weight | 394.63200 |
Flash Point | 221ºC |
Exact Mass | 394.32400 |
PSA | 20.23000 |
LogP | 7.25090 |
Index of Refraction | 1.553 |
Storage condition | 20°C |
Lipid droplet changes in proliferating and quiescent 3T3 fibroblasts.
Histochem. Cell Biol. 129(5) , 611-21, (2008) Lipid droplets (LDs) are fat-storing organelles present in virtually all eukaryotic cells and involved in many aspects of cell biology related to lipid metabolism and cholesterol homeostasis. In this ... |
|
Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells.
Histochem. Cell Biol. 130(5) , 891-908, (2008) Distribution and dynamics of cholesterol in the plasma membrane as well as internalization pathways for sterol from the cell surface are of great cell biological interest. Here, UV-sensitive wide fiel... |
|
Quantitative assessment of sterol traffic in living cells by dual labeling with dehydroergosterol and BODIPY-cholesterol.
Chem. Phys. Lipids 164(3) , 221-35, (2011) Cholesterol with BODIPY at carbon-24 of the side chain (BCh2) has recently been introduced as new cholesterol probe with superior fluorescence properties. We compare BCh2 with the intrinsically fluore... |
Dehydroergosterol |
ergosta-5,7,9(11),22-tetraen-3ß-ol |
(3S,10S,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,12,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol |
Ergosta-5,7,9(11),22-tetraen-3β-ol |