Thidiazuron

Modify Date: 2024-01-02 18:03:15

Thidiazuron Structure
Thidiazuron structure
Common Name Thidiazuron
CAS Number 51707-55-2 Molecular Weight 220.25
Density 1.5±0.1 g/cm3 Boiling Point 410.5±55.0 °C at 760 mmHg
Molecular Formula C9H8N4OS Melting Point 213°C
MSDS Chinese USA Flash Point 202.1±31.5 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of Thidiazuron


Thidiazuron is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name thidiazuron
Synonym More Synonyms

 Thidiazuron Biological Activity

Description Thidiazuron is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro Thidiazuron 是一种植物生长调节剂,用作 Murashige 和 Skoog 培养基等培养基的补充剂,用于微繁殖。Thidiazuron 促进植物器官发生(芽再生)和植物再生。

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 410.5±55.0 °C at 760 mmHg
Melting Point 213°C
Molecular Formula C9H8N4OS
Molecular Weight 220.25
Flash Point 202.1±31.5 °C
Exact Mass 220.041885
PSA 95.15000
LogP 1.81
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.722

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU1395000
CHEMICAL NAME :
Urea, 1-phenyl-3-(1,2,3-thiadiazol-5-yl)-
CAS REGISTRY NUMBER :
51707-55-2
LAST UPDATED :
199612
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C9-H8-N4-O-S
MOLECULAR WEIGHT :
220.27
WISWESSER LINE NOTATION :
T5NNSJ DMVMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5350 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2300 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,813,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C118,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3740 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
7100 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,813,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2813 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,813,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
31892 mg/kg/17W-I
TOXIC EFFECTS :
Endocrine - evidence of thyroid hypofunction Blood - methemoglobinemia-carboxyhemoglobin Blood - changes in erythrocyte (RBC) count
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32207 mg/kg/43W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
813 mg/kg
SEX/DURATION :
male 76 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(1),72,1984 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H315-H319-H335-H410
Precautionary Statements P273-P305 + P351 + P338-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S26-S36
RIDADR UN 3077 9 / PGIII
WGK Germany 3
RTECS YU1395000

 Articles31

More Articles
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and keto...

Role of TDZ in the quick regeneration of multiple shoots from nodal explant of Vitex trifolia L.--an important medicinal plant.

Appl. Biochem. Biotechnol. 168(5) , 957-66, (2012)

The effect of thidiazuron (TDZ) has been investigated in shoot multiplication for a simple, efficient, rapid, and commercially applicable regeneration protocol of an important medicinal plant, Vitex t...

Changes of gentiopicroside synthesis during somatic embryogenesis in Gentiana macrophylla.

Planta Med. 75 , 1618-1624, (2009)

IN VITRO plant regeneration of Gentiana macrophylla Pall. and determination of gentiopicroside content during somatic embryogenesis are described in the present work. The highest percentage of embryog...

 Synonyms

1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea
1-phenyl-3-(thiadiazol-5-yl)urea
Methanol, 1-(phenylimino)-1-(1,2,3-thiadiazol-5-ylamino)-, (E)-
Thidiazuron
Urea, N-phenyl-N'-1,2,3-thiadiazol-5-yl-
N-phenyl-N’-1,2,3-thiadiazol-5-ylurea
MFCD00078723
EINECS 257-356-7
N'-Phenyl-N-1,2,3-thiadiazol-5-ylcarbamimidic acid
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