Dimidium bromide

Modify Date: 2024-01-02 13:50:20

Dimidium bromide Structure
Dimidium bromide structure
Common Name Dimidium bromide
CAS Number 518-67-2 Molecular Weight 380.281
Density N/A Boiling Point N/A
Molecular Formula C20H18BrN3 Melting Point 243-248 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Dimidium bromide


Dimidium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name Dimidium bromide
Synonym More Synonyms

 Dimidium bromide Biological Activity

Description Dimidium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Melting Point 243-248 °C(lit.)
Molecular Formula C20H18BrN3
Molecular Weight 380.281
Exact Mass 379.068390
PSA 55.92000
LogP 1.81530
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SF7960500
CHEMICAL NAME :
Phenanthridinium, 3,8-diamino-5-methyl-6-phenyl-, bromide
CAS REGISTRY NUMBER :
518-67-2
LAST UPDATED :
199512
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H18-N3.Br
MOLECULAR WEIGHT :
380.32
WISWESSER LINE NOTATION :
T B666 HKJ EZ H1 IR& LZ &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
61 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,65,1946
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 5,261,1950 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
10 mg/kg/5D-I
TOXIC EFFECTS :
Liver - fatty liver degeneration
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,65,1946 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6236 No. of Facilities: 34 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 67 (estimated) No. of Female Employees: 34 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR 2811
WGK Germany 3
RTECS SF7960500
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933990090

 Synthetic Route

~%

Dimidium bromide Structure

Dimidium bromide

CAS#:518-67-2

Literature: Barber et al. Journal of the Society of Chemical Industry, London, 1950 , vol. 69, p. 82,92

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

More Articles
A comparison of the base-pair specificities of three phenanthridine drugs using solution spectroscopy.

Int. J. Biochem. 14 , 493, (1982)

1. The absorption spectrum of three phenanthridine drugs (ethidium, dimidium and prothidium bromide) bound to natural DNAs of differing G-C content were obtained using a novel mixing scheme and analys...

[Effect of some DNA-intercalators and antioxidants on the phagosome- lysosome fusion and F-actin content in murine peritoneal macrophages].

Tsitologiia 40(6) , 585-90, (1998)

Effect of DNA-intercalators ethidium bromide (EB, 0.005 and 0.015 mM) and dimidium bromide (DB, 0.005 and 0.010 mM) and antioxidative compounds acetylsalicylic acid (ASA, 0.05 and 0.50 mM) and beta-ca...

[The toxicity of sanguinarine compared to a number of other DNA-tropic compounds for ethidium bromide-sensitive and -resistant transformed murine fibroblasts in culture].

Tsitologiia 31(11) , 1363-8, (1989)

A natural DNA-intercalator plant benzo-c-phenanthridine alkaloid sanguinarine is more toxic for mouse transformed fibroblast L-cells in culture than synthetic DNA-intercalator ethidium bromide (EtB) a...

 Synonyms

Dimidiniumbromide
Phenanthridinium1553
DiMidiuM BroMide
DIMIDIUM BROMIDE 1/2 H2O
Phenanthridinium, 3,8-diamino-5-methyl-6-phenyl-, bromide (1:1)
3,8-Diamino-5-methyl-6-phenylphenanthridinium bromide Trypadine
3,8-Diamino-5-methyl-6-phenylphenanthridinium bromide
3,8-diamino-5-methyl-6-phenyl-phenanthridinium,bromide
MFCD00011757
Phenanthridiniumcompound1553
6c46
EINECS 208-256-7
TRYPADINE
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