2,4(1H,3H)-Pyrimidinedione,5-[bis(2-chloroethyl)amino]-6-methyl-

MOLECULAR FORMULA :

C9-H13-Cl2-N3-O2

MOLECULAR WEIGHT :

266.15

WISWESSER LINE NOTATION :

T6MVMVJ EN2G2G F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2400 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 mg/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Primate - monkey Kidney

DOSE/DURATION :

100 mg/L

REFERENCE :

TSITAQ Tsitologiya. Cytology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1959- Volume(issue)/page/year: 15,1505,1973