Anti-Influenza agent 4

Modify Date: 2024-07-17 16:31:20

Anti-Influenza agent 4 Structure
Anti-Influenza agent 4 structure
Common Name Anti-Influenza agent 4
CAS Number 522625-85-0 Molecular Weight 386.42
Density N/A Boiling Point N/A
Molecular Formula C19H18N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-Influenza agent 4


Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1].

 Names

Name Benzamide, N-[3-[[(2-furanylmethyl)amino]sulfonyl]phenyl]-4-methoxy-

 Anti-Influenza agent 4 Biological Activity

Description Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively[1].
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Target

EC50: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)[1]

In Vitro Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells[1]. Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC50s of 150±0.07 nM and 62±0.02 nM, respectively[1]. Anti-Influenza agent 4 shows IC50s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay[1]. Cell Cytotoxicity Assay[1] Cell Line: MDCK cells Concentration: 0-500 μM Incubation Time: 24 and 48 h Result: Exhibited low cytotoxicity with a CC50 value of 450 μM.

 Chemical & Physical Properties

Molecular Formula C19H18N2O5S
Molecular Weight 386.42
Storage condition -20°C
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